Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Ift80tm1.1Syy
Name:	intraflagellar transport 80; targeted mutation 1.1, Shuying Yang
MGI ID:	MGI:5818514
Synonyms:	IFT80f
Gene:	Ift80  Location: Chr3:68799832-68911892 bp, - strand  Genetic Position: Chr3, 32.07 cM, cytoband E2
Alliance:	Ift80tm1.1Syy page

Germline Transmission:	Earliest citation of germline transmission: J:237888
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6N

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: Exon 6 was flanked with loxP sites and an FRT site flanked marker and selection double cassette was inserted into intron 5. The double cassette consists of a beta galactosidase (LacZ) gene cassette and a neomycin resistance gene cassette, separated by a loxP site. The marker-selection cassette was deleted through flp-mediated recombination, leaving a conditional ready allele with a floxed exon 6. (J:236749, J:237888)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ift80 Mutation:	56 strains or lines available

Original:	J:237888 Yuan X, et al., Deletion of IFT80 Impairs Epiphyseal and Articular Cartilage Formation Due to Disruption of Chondrocyte Differentiation. PLoS One. 2015;10(6):e0130618
All:	4 reference(s)