Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Hhextm1(cre/Esr1*)Sia
Name:	hematopoietically expressed homeobox; targeted mutation 1, Shinich Aizawa
MGI ID:	MGI:5817778
Synonyms:	HhexCreERTM
Gene:	Hhex  Location: Chr19:37423289-37429179 bp, + strand  Genetic Position: Chr19, 32.28 cM, cytoband D1
Alliance:	Hhextm1(cre/Esr1*)Sia page

Germline Transmission:	Earliest citation of germline transmission: J:222398
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Hhextm1(cre/Esr1*)Sia expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Hhex (MGI:96086)   Mutation details: The targeting vectors were constructed with the RP23-348B20 BAC clone. A CreERTM fusion protein carrying a polyA sequence and an FRT-flanked PGK-Neo cassette are inserted into the first exon of Hhex gene. (J:222398)

Activity:	Tissue activity of this recombinase allele
Driver:	Hhex (mouse) Summary of all recombinase alleles driven by Hhex. Alliance mouse Hhex gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hhex Mutation:	16 strains or lines available

Original:	J:222398 Hoshino H, et al., AVE protein expression and visceral endoderm cell behavior during anterior-posterior axis formation in mouse embryos: Asymmetry in OTX2 and DKK1 expression. Dev Biol. 2015 Jun 15;402(2):175-91
All:	1 reference(s)