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Gene Expression Data
Assay Details
Assay
Reference: J:17838 Lyn S, et al., Localization of CRABP-I and CRABP-II mRNA in the early mouse embryo by whole-mount in situ hybridization: implications for teratogenesis and neural development. Dev Dyn. 1994 Apr;199(4):280-91
Assay type: RNA in situ
MGI Accession ID: MGI:5817015
Gene symbol: Crabp1
Gene name: cellular retinoic acid binding protein I
Probe: CRABP-I cDNA5
Probe preparation: Antisense RNA
Results
Specimen 1H: embryonic day 8.0 (more )
Note: 4-6 somites
Structure Level Pattern Image Note
TS12: rhombomere Strong Regionally restricted 1H Expressed strongly in the neuroepithelium of the caudal three-quarters of rhombomere B and the rostral third of rhombomere C.
TS12: head mesenchyme Present 1H Lower expression.
TS12: lateral plate mesoderm Present 1H Lower expression.

Specimen 1I: embryonic day 8.0 (more )
Note: 4-6 somites
Structure Level Pattern Image Note
TS12: rhombomere Strong Regionally restricted 1I Expressed strongly in the neuroepithelium of the caudal three-quarters of rhombomere B and the rostral third of rhombomere C.
TS12: head mesenchyme Present 1I Lower expression.
TS12: lateral plate mesoderm Present 1I Lower expression.

Specimen 2A: embryonic day 8.0 (more )
Note: 7 somites
Structure Level Pattern Image Note
TS12: neural crest Strong Regionally restricted 2A Expressed in presumptive neural crest cells at the dorsal edge of the neural folds extending caudally from rhombomere 6 over the anterior presomitic region.
TS12: future hindbrain Weak Regionally restricted 2A A gradient expression at a low level in the neuroepithelium of rhombomere 2 and decreasing through the rostral hindbrain.

Specimen 2B: embryonic day 8.0 (more )
Note: 7 somites
Structure Level Pattern Image Note
TS12: neural crest Strong Regionally restricted 2B Expressed in presumptive neural crest cells at the dorsal edge of the neural folds extending caudally from rhombomere 6 over the anterior presomitic region.
TS12: future hindbrain Weak Regionally restricted 2B A gradient expression at a low level in the neuroepithelium of rhombomere 2 and decreasing through the rostral hindbrain.

Specimen 2C: embryonic day 8.5 (more )
Note: 8-9 somites
Structure Level Pattern Image Note
TS13: rhombomere 4 Strong 2C
TS13: rhombomere 5 Strong 2C
TS13: posterior pro-rhombomere Strong 2C Expressed in rhombomere 6.
TS13: 1st branchial arch Weak 2C Low expression in a band extending from rhombomere 2 to the first branchial arch.
TS13: 2nd branchial arch Present 2C Expressed in a band of higher expression extended from rhombomere 4 to the second arch.
TS13: branchial arch Present Regionally restricted 2C Expressed in a band of higher expression extended from rhombomere 6 to the third arch.
TS13: head mesenchyme Weak 2C
TS13: lateral plate mesoderm Weak 2C

Specimen 2D: embryonic day 8.5 (more )
Note: 8-9 somites
Structure Level Pattern Image Note
TS13: rhombomere 4 Strong 2D
TS13: rhombomere 5 Strong 2D
TS13: future hindbrain Weak Regionally restricted 2D A gradient expression at a low level in the neuroepithelium of rhombomere 2 and decreasing through the rostral hindbrain.
TS13: posterior pro-rhombomere Strong 2D Expressed in rhombomere 6.
TS13: 1st branchial arch Weak 2D Low expression in a band extending from rhombomere 2 to the first branchial arch.
TS13: 2nd branchial arch Present 2D Expressed in a band of higher expression extended from rhombomere 4 to the second arch.
TS13: branchial arch Present Regionally restricted 2D Expressed in a band of higher expression extended from rhombomere 6 to the third arch.
TS13: head mesenchyme Weak 2D
TS13: lateral plate mesoderm Weak 2D

Specimen 2F: embryonic day 9.0 (more )
Note: 13-14 somites
Structure Level Pattern Image Note
TS14: rhombomere 4 Strong 2F
TS14: rhombomere 5 Strong 2F
TS14: rhombomere 6 Strong 2F
TS14: 1st branchial arch Weak 2F Low expression in a band extending from rhombomere 2 to the first branchial arch.
TS14: 2nd branchial arch Present 2F Expressed in a band of higher expression extended from rhombomere 4 to the second arch.
TS14: 3rd branchial arch Present 2F Expressed in a band of higher expression extended from rhombomere 6 to the third arch.

Specimen 2G: embryonic day 9.5 (more )
Note: 24-28 somites
Structure Level Pattern Image Note
TS15: 2nd branchial arch Present 2G
TS15: 3rd branchial arch Present 2G
TS15: diencephalon Strong Regionally restricted 2G Expressed in the caudal half.
TS15: future midbrain Strong Regionally restricted 2G Expressed in the dorsal mesencephalon.
TS15: fronto-nasal process mesenchyme Strong 2G
TS15: rhombomere 1 Strong 2G
TS15: rhombomere 2 Strong 2G
TS15: 1st branchial arch mandibular component Trace 2G Barely detectable.

Specimen 2H: embryonic day 9.5 (more )
Note: 28-30 somites
Structure Level Pattern Image Note
TS15: diencephalon Strong Regionally restricted 2H Expressed in the caudal half.
TS15: future midbrain Strong Regionally restricted 2H Expressed in the dorsal mesencephalon.
TS15: fronto-nasal process mesenchyme Strong 2H
TS15: rhombomere 1 Strong 2H
TS15: rhombomere 2 Strong 2H
TS15: forelimb bud Weak Uniform 2H
TS15: 1st branchial arch mandibular component Trace 2H Barely detectable.


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory