About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:15507 Dolle P, et al., Disruption of the Hoxd-13 gene induces localized heterochrony leading to mice with neotenic limbs. Cell. 1993 Nov 5;75(3):431-41
Assay type: RNA in situ
MGI Accession ID: MGI:5816729
Gene symbol: Hoxd13
Gene name: homeobox D13
Probe: probe A
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 5A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: footplate Present Regionally restricted 5A Authors report strong and sharply defined expression in the extremities of both fore- and hindlimbs.
TS19: handplate Present Regionally restricted 5A Authors report strong and sharply defined expression in the extremities of both fore- and hindlimbs.

Specimen 5B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: foot Present Regionally restricted 5B Authors report strong and sharply defined expression in the extremities of both fore- and hindlimbs.
TS20: hand Present Regionally restricted 5B Authors report strong and sharply defined expression in the extremities of both fore- and hindlimbs.

Specimen 5C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hand mesenchyme Present Regionally restricted 5C Expression restricted to the perichondrium.
TS20: forelimb digit 1 Absent 5C Expression domain not extended to digit 1 anlage.
TS20: hand epithelium Absent 5C Ectodermal layer is negative for expression.

Specimen 5D: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: foot mesenchyme Present Regionally restricted 5D Expression in most of posterior-distal mesenchymal cells.
TS20: hindlimb digit 1 Absent 5D Expression domain not extended to digit 1 anlage.

Specimen not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: forelimb digit 1 Present Regionally restricted In older handplates, expression detected up to area of prospective digit 1.
TS22: hand mesenchyme Present Regionally restricted Expression domain restricted to perichondrium.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/21/2024
MGI 6.23
The Jackson Laboratory