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Tg(Npas1-icre,-tdTomato)1Cschn
Transgene Detail
Summary
Symbol: Tg(Npas1-icre,-tdTomato)1Cschn
Name: transgene insertion 1, C Savio Chan
MGI ID: MGI:5816528
Synonyms: Npas1Cre-2A-tdTomato, Npas1- Cre-2A-tdTomato, Npas1- Cre-2A-tdTomato BAC transgenic line 1, Npas1-tdTom
Transgene: Tg(Npas1-icre,-tdTomato)1Cschn  Location: unknown  
Alliance: Tg(Npas1-icre,-tdTomato)1Cschn page
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Recombinase, Reporter)
Mutation:    Insertion
 
Tg(Npas1-icre,-tdTomato)1Cschn expression driven by 1 gene
 
Mutation detailsA mouse bacterial artificial chromosome (BAC) containing the entire Npas1 gene, was modified by inserting iCre-2A (cleavable fusion peptide sequence)-tdTomato and polyadenylation sequence from bovine growth hormone downstream of the ATG translation initiation codon, and removing Npas1 coding sequence. A transgenic insert made from this modified BAC was microinjected into the pronucleus of C57BL/6 fertilized eggs. The resulting Npas1-tdTom transgenic mice from founder line 1 were subsequently maintained on the C57BL/6J background. (J:237688)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Npas1 (mouse)
Summary of all recombinase alleles driven by Npas1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:237688 Hernandez VM, et al., Parvalbumin+ Neurons and Npas1+ Neurons Are Distinct Neuron Classes in the Mouse External Globus Pallidus. J Neurosci. 2015 Aug 26;35(34):11830-47
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory