Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Rai1tm1Luo
Name:	retinoic acid induced 1; targeted mutation 1, Liqun Luo
MGI ID:	MGI:5816453
Synonyms:	Rai1Tag, Rai1-Tag
Gene:	Rai1  Location: Chr11:59995839-60090023 bp, + strand  Genetic Position: Chr11, 37.81 cM, cytoband B2
Alliance:	Rai1tm1Luo page

Germline Transmission:	Earliest citation of germline transmission: J:237687
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S1/Sv

Allele Type:    Targeted (Conditional ready, Reporter) Mutation:    Insertion   Mutation details: The targeting vector contains a loxP-flanked FLAG-myc-STOP cassette upstream of an EGFP sequence, all inserted in-frame into the endogenous stop codon. Prior to Cre recombinase exposure, expression of FLAG/myc-tagged RAI1 is observed in a pattern consistent with the endogenous gene, and no EGFP expression is reported. (J:237687)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rai1 Mutation:	73 strains or lines available

Original:	J:237687 Huang WH, et al., Molecular and Neural Functions of Rai1, the Causal Gene for Smith-Magenis Syndrome. Neuron. 2016 Oct 19;92(2):392-406
All:	1 reference(s)