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Gene Expression Data
Assay Details
Assay
Reference: J:117267 Sarkisian MR, et al., MEKK4 signaling regulates filamin expression and neuronal migration. Neuron. 2006 Dec 7;52(5):789-801
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5812524
Gene symbol: Flna
Gene name: filamin, alpha
Antibody: anti-FLNa
Detection system: Secondary antibody
Results
Specimen 5E upper: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: cerebral cortex intermediate zone Present 5E upper
TS25: cortical plate Present 5E upper
TS25: brain blood vessel Present 5E upper
TS25: cerebral cortex Present 5E upper Expression was low in the proliferative zone and higher in the intermediate zone. Microglia and blood vessels were also labeled.

Specimen 5E lower: embryonic day 17.5; Map3k4tm1Flv/Map3k4tm1Flv (more )
Note: slightly enlarged forebrain mutant sample
Structure Level Pattern Image Note
TS25: cerebral cortex Present 5E lower Expression persisted to the proliferative zone surface at sites of periventricular heterotopia.
TS25: cerebral cortex ventricular zone Strong 5E lower Expressed abnormally high levels in the cells along the surface, particularly at sites where the integrity of the surface appeared disrupted.

Specimen S6A left: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: cerebral cortex intermediate zone Strong S6A left
TS25: cortical plate Strong S6A left
TS25: brain blood vessel Present S6A left

Specimen S6A right: embryonic day 17.5; Map3k4tm1Flv/Map3k4tm1Flv (more )
Structure Level Pattern Image Note
TS25: cerebral cortex Present S6A right Expression persisted to the proliferative zone surface at sites of periventricular heterotopia.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory