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Gene Expression Data
Assay Details
Assay
Reference: J:117267 Sarkisian MR, et al., MEKK4 signaling regulates filamin expression and neuronal migration. Neuron. 2006 Dec 7;52(5):789-801
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5812479
Gene symbol: Tubb3
Gene name: tubulin, beta 3 class III
Antibody: anti-Tuj1
Detection system: Secondary antibody
Results
Specimen 1E left: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: forebrain Present 1E left Expressed in neuronal cells.
TS26: forebrain ventricular layer Absent 1E left

Specimen 1E right: embryonic day 18.5; Map3k4tm1Flv/Map3k4tm1Flv (more )
Note: slightly enlarged forebrain mutant sample
Structure Level Pattern Image Note
TS26: forebrain Strong 1E right Expressed in neuronal cells. Many periventricular heterotopia cells were intensely labeled.
TS26: forebrain ventricular layer Present Regionally restricted 1E right Expressed in periventricular heterotopia cells protruding into the lateral ventricle.

Specimen 1F: embryonic day 18.5; Map3k4tm1Flv/Map3k4tm1Flv (more )
Note: highly degenerated forebrain mutant sample
Structure Level Pattern Image Note
TS26: forebrain Strong 1F Expressed in neuronal cells. Many periventricular heterotopia cells were intensely labeled.
TS26: forebrain ventricular layer Strong Regionally restricted 1F Expressed in periventricular heterotopia cells protruding into the lateral ventricle.

Specimen 1G: embryonic day 18.5; Map3k4tm1Flv/Map3k4tm1Flv (more )
Note: highly degenerated forebrain mutant sample
Structure Level Pattern Image Note
TS26: forebrain Strong 1G Expressed in neuronal cells. Also expressed in ectopias.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory