Rhobtb3 In situ reporter (knock in) Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:226884 Lutz J, et al., Expression analysis of mouse Rhobtb3 using a LacZ reporter and preliminary characterization of a knockout strain. Histochem Cell Biol. 2014 Nov;142(5):511-28
Assay type:	In situ reporter (knock in)
MGI Accession ID:	MGI:5812322
Gene symbol:	Rhobtb3
Gene name:	Rho-related BTB domain containing 3

Reporter:	lacZ
	Direct Detection
Assay notes:	Fixative was 0.2 % glutaraldehyde.

Results

Specimen 2a: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

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Structure	Level	Image
TS26: bone	Strong	2a
TS26: cartilage	Strong	2a
TS26: skeletal muscle tissue	Strong	2a
TS26: smooth muscle tissue	Strong	2a

Specimen 2b: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS26: bone	Strong		2b
TS26: cartilage	Strong		2b
TS26: esophagus muscularis	Strong		2b
TS26: laryngeal cartilage	Strong		2b
TS26: skeletal muscle tissue	Strong		2b
TS26: smooth muscle tissue	Strong		2b
TS26: esophagus mucosa	Strong	Regionally restricted	2b	Expression is in the submucosa.
TS26: larynx muscle	Present		2b
TS26: larynx	Present	Regionally restricted	2b	Expression is in the submucosa, weak in the epithelium.
TS26: thymus	Weak	Regionally restricted	2b	Expression is in lymphatic tissue.
TS26: lymphatic system	Weak	Regionally restricted	2b	There is scattered expression in the lymphatic tissue of the tonsil.
TS26: oral region	Weak	Regionally restricted	2b	There is scattered expression in the lymphatic tissue of the tonsil.
TS26: esophagus epithelium	Weak		2b

Specimen 2c: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

)

Structure	Level	Image
TS26: atrium cardiac muscle	Strong	2c
TS26: rib	Strong	2c
TS26: ventricle cardiac muscle	Strong	2c

Specimen 2d: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

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Structure	Level	Pattern	Image	Note
TS26: blood vessel smooth muscle	Strong		2d	Shown are renal vessels.
TS26: tunica media	Strong		2d	Shown are renal vessels.
TS26: renal capsule	Strong		2d
TS26: glomerular tuft	Moderate		2d
TS26: liver	Weak	Single cells	2d	Expression is in very few scattered unidentified cells.

Specimen 2e: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS26: intestine muscularis	Strong		2e
TS26: intestine mucosa	Strong	Regionally restricted	2e	Expression is in the submucosa.
TS26: seminiferous cord	Strong	Regionally restricted	2e	Expression is in the epithelium.
TS26: ductus deferens	Present	Regionally restricted	2e	Expression is in the epithelium and muscle layer.
TS26: intestine epithelium	Weak		2e

Specimen 3a: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS26: ventricle cardiac muscle	Strong		3a

Specimen 3b: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS26: atrium cardiac muscle	Strong		3b

Specimen 3c: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS26: blood vessel smooth muscle	Strong		3c
TS26: tunica media	Strong		3c

Specimen 3d: postnatal week 10; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

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Structure	Level	Pattern	Image	Note
TS28: ventricle cardiac muscle	Present		3d

Specimen 3e: postnatal week 10; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

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Structure	Level	Pattern	Image	Note
TS28: atrium cardiac muscle	Present		3e

Specimen 3f: postnatal week 10; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS28: blood vessel smooth muscle	Present		3f
TS28: tunica media	Present		3f

Specimen 3g: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS26: respiratory system smooth muscle	Strong		3g
TS26: respiratory system epithelium	Present	Scattered	3g
TS26: respiratory system vascular element	Present	Regionally restricted	3g	Expression is throughout the adventitia.

Specimen 3h: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

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Structure	Level	Pattern	Image	Note
TS26: diaphragm	Strong	Regionally restricted	3h	Expression is in skeletal muscle.
TS26: pleura	Present	Diffuse	3h

Specimen 3i: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

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Structure	Level	Pattern	Image	Note
TS26: thymus	Weak	Regionally restricted	3i	Expression is in the lymphatic tissue.

Specimen 4a: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS26: stomach mucosa	Strong	Regionally restricted	4a	Expression is in the submucosa.
TS26: stomach muscularis externa	Strong		4a
TS26: stomach epithelium	Weak		4a

Specimen 4b: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

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Structure	Level	Pattern	Image	Note
TS26: intestine mucosa	Strong	Regionally restricted	4b	Expression is in the submucosa.
TS26: intestine muscularis	Strong		4b
TS26: intestine epithelium	Weak		4b

Specimen 4c: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

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Structure	Level	Pattern	Image	Note
TS26: bladder	Present	Regionally restricted	4c	Expression is in the submucosa.
TS26: detrusor muscle of bladder	Present		4c

Specimen 4d: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS26: liver	Weak	Single cells	4d	Expression is in very few scattered unidentified cells.

Specimen 4e: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS26: pancreatic duct	Strong	Regionally restricted	4e	Expression is in the epithelium.
TS26: pancreatic acinus	Strong		4e
TS26: pancreas	Strong	Regionally restricted	4e	Expression is in tissue surrounding the ducts.

Specimen 4f: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

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Structure	Level	Pattern	Image	Note
TS26: adrenal gland	Present	Regionally restricted	4f	Expression is in the capsule.
TS26: adrenal cortex	Present	Scattered	4f
TS26: adrenal medulla	Present	Scattered	4f

Specimen 4g: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

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Structure	Level	Pattern	Image	Note
TS26: renal capsule	Strong		4g
TS26: glomerular tuft	Moderate		4g

Specimen 4h: postnatal week 10; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

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Structure	Level	Image
TS28: glomerular tuft	Weak	4h
TS28: renal cortex	Weak	4h
TS28: renal medullary capillary	Weak	4h

Specimen 4i: postnatal week 10; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS28: renal medulla	Weak		4i

Specimen 4j: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS26: ductus deferens	Present	Regionally restricted	4j	Expression is in the epithelium and muscle layer.

Specimen 4k: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS26: seminiferous cord	Strong	Regionally restricted	4k	Expression is in the epithelium.

Specimen 4l: postnatal week 10; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS28: seminiferous tubule	Strong	Regionally restricted	4l	Expression is in the epithelium.

Specimen 5a: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS26: oral epithelium	Weak	Scattered	5a
TS26: oral mucosa	Weak	Scattered	5a	Expression is in the submucosa.

Specimen 5b: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

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Structure	Level	Pattern	Image	Note
TS26: salivary gland	Present	Regionally restricted	5b	Scattered expression in acini and connective tissue.

Specimen 5c: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS26: lymphatic system	Present	Scattered	5c	Expression is in lymphatic tissue of the tonsil.
TS26: oral region	Present	Scattered	5c	Expression is in lymphatic tissue of the tonsil.

Specimen 5d: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

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Structure	Level	Pattern	Image	Note
TS26: enamel organ	Moderate	Regionally restricted	5d	Expression is in the inner enamel epithelium.

Specimen 5f: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS26: esophagus muscularis	Strong		5f
TS26: esophagus mucosa	Strong	Regionally restricted	5f	Expression is in the submucosa.
TS26: esophagus epithelium	Weak		5f

Specimen 5g: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

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Structure	Level	Pattern	Image	Note
TS26: laryngeal cartilage	Strong		5g
TS26: larynx muscle	Present		5g
TS26: larynx	Present	Regionally restricted	5g	Expression is in the submucosa.

Specimen 5h: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

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Structure	Level	Pattern	Image	Note
TS26: vibrissa follicle	Weak		5h

Specimen 5i: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

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Structure	Level	Pattern	Image	Note
TS26: dermis	Weak		5i
TS26: epidermis basal layer	Weak		5i

Specimen 6a: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

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Structure	Level	Pattern	Image	Note
TS26: retina layer	Strong	Regionally restricted	6a	Expression is in ganglion cells.
TS26: sclera	Strong		6a

Specimen 6b: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

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Structure	Level	Pattern	Image	Note
TS26: retina layer	Strong	Regionally restricted	6b	Expression is in ganglion cells.
TS26: sclera	Strong		6b

Specimen 6c: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

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Structure	Level	Pattern	Image	Note
TS26: sclera	Strong		6c

Specimen 6d: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

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Structure	Level	Pattern	Image	Note
TS26: crista ampullaris	Present	Regionally restricted	6d	Expression is in the sensory epithelium.
TS26: organ of Corti	Present

Specimen 6e: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

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Structure	Level	Pattern	Image	Note
TS26: crista ampullaris	Present	Regionally restricted	6e	Expression is in the sensory epithelium.

Specimen 6f: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

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Structure	Level	Pattern	Image	Note
TS26: organ of Corti	Present		6f

Specimen 6g: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

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Structure	Level	Pattern	Image	Note
TS26: cochlear ganglion	Strong		6g
TS26: vestibulocochlear nerve cochlear component	Strong		6g
TS26: organ of Corti	Present		6g
TS26: crista ampullaris	Present	Regionally restricted	6g	Expression is in the sensory epithelium.

Specimen 6h: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

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Structure	Level	Pattern	Image	Note
TS26: cochlear ganglion	Very strong		6h

Specimen 6i: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

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Structure	Level	Pattern	Image	Note
TS26: vestibulocochlear nerve cochlear component	Strong		6i

Specimen 6j: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

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Structure	Level	Pattern	Image	Note
TS26: ethmoid bone	Strong		6j
TS26: nasal septum cartilage	Strong		6j
TS26: olfactory epithelium	Weak		6j
TS26: nasal cavity mucosa	Weak	Regionally restricted	6j	Expression is in the submucosa.

Specimen 6k: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

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Structure	Level	Pattern	Image	Note
TS26: ethmoid bone	Strong		6k
TS26: nasal septum cartilage	Strong		6k

Specimen 6l: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS26: olfactory epithelium	Weak		6l
TS26: nasal cavity mucosa	Weak	Regionally restricted	6l	Expression is in the submucosa.

Specimen S2a: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

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Structure	Level	Pattern	Image	Note
TS26: cerebellum	Weak	Single cells	S2a' , S2a
TS26: hindbrain meninges	Present		S2a' , S2a

Specimen S2b: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS26: choroid plexus	Moderate	Regionally restricted	S2b' , S2b	Expression is in the intermediate part of the choroid plexus.

Specimen S2c: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

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Structure	Level	Pattern	Image	Note
TS26: superior colliculus	Weak	Single cells	S2c' , S2c

Specimen S2d: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

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Structure	Level	Pattern	Image	Note
TS26: inferior colliculus	Weak	Single cells	S2d' , S2d	Expression is in very few scattered cells.

Specimen S2e: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS26: medulla oblongata	Strong	Regionally restricted	S2e , S2e'

Specimen S2f: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS26: pons	Weak	Single cells	S2f , S2f'	Expression is in a few scattered cells.

Specimen S2g: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS26: neocortex	Absent		S2g' , S2g

Specimen S2h: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS26: hippocampus	Strong	Regionally restricted	S2h , S2h'	Expression is in the cortical area.

Specimen S2i: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS26: thalamus	Present	Regionally restricted	S2i , S2i'

Specimen S2j: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

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Structure	Level	Pattern	Image	Note
TS26: choroid plexus	Weak		S2j' , S2j
TS26: corpus striatum	Trace		S2j , S2j'

Specimen S2k: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

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Structure	Level	Image
TS26: pituitary gland	Strong	S2k' , S2k''' , S2k , S2k''
TS26: adenohypophysis pars intermedia	Strong	S2k , S2k'
TS26: neurohypophysis	Present	S2k , S2k''
TS26: adenohypophysis pars anterior	Present	S2k , S2k'''

Specimen Table 1 E19: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

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Structure	Level	Pattern	Note
TS26: bone	Very strong
TS26: cartilage	Very strong
TS26: cochlear ganglion	Very strong
TS26: detrusor muscle of bladder	Very strong
TS26: intestine muscularis	Very strong
TS26: laryngeal cartilage	Very strong
TS26: stomach muscularis externa	Very strong
TS26: trachea cartilaginous ring	Very strong
TS26: tunica media	Very strong
TS26: vestibulocochlear nerve cochlear component	Very strong
TS26: larynx	Strong	Regionally restricted	Expression is in the submucosa and muscularis and is moderate in the epithelium.
TS26: adenohypophysis pars intermedia	Strong
TS26: atrium cardiac muscle	Strong
TS26: esophagus muscularis	Strong
TS26: pancreatic acinus	Strong
TS26: pancreatic duct	Strong
TS26: pleura	Strong
TS26: renal capsule	Strong
TS26: respiratory system smooth muscle	Strong
TS26: sclera	Strong
TS26: seminiferous cord	Strong
TS26: skeletal muscle tissue	Strong
TS26: ventricle cardiac muscle	Strong
TS26: medulla oblongata	Strong	Regionally restricted
TS26: enamel organ	Strong	Regionally restricted	Expression is in the inner enamel epithelium.
TS26: inner ear epithelium	Strong	Regionally restricted	Expression is in sensory epithelium.
TS26: trachea	Strong	Regionally restricted	Expression is in the submucosa and muscularis.
TS26: esophagus mucosa	Strong	Regionally restricted	Expression is in the submucosa.
TS26: intestine mucosa	Strong	Regionally restricted	Expression is in the submucosa.
TS26: stomach mucosa	Strong	Regionally restricted	Expression is in the submucosa.
TS26: bladder	Strong	Regionally restricted	Expression is in the submucosa and weak in the epithelium.
TS26: retina layer	Strong	Regionally restricted	Expression is in ganglion cells.
TS26: adenohypophysis pars anterior	Moderate
TS26: choroid plexus	Moderate
TS26: esophagus epithelium	Moderate
TS26: glomerular tuft	Moderate
TS26: intestine epithelium	Moderate
TS26: meninges	Moderate
TS26: neurohypophysis	Moderate
TS26: olfactory epithelium	Moderate
TS26: oral epithelium	Moderate
TS26: thalamus	Moderate
TS26: trachea epithelium	Moderate
TS26: nasal cavity mucosa	Moderate	Regionally restricted	Expression is in the submucosa.
TS26: oral mucosa	Moderate	Regionally restricted	Expression is in the submucosa.
TS26: salivary gland	Moderate	Regionally restricted	Expression is in the acini and connective tissue.
TS26: adrenal gland	Moderate	Regionally restricted	Expression is in the capsule.
TS26: ductus deferens	Moderate	Regionally restricted	Expression is in the epithelium and muscularis.
TS26: spinal cord	Moderate	Regionally restricted
TS26: oral region	Moderate	Single cells	Expression is in unidentified cells in the tonsil.
TS26: adrenal cortex	Weak
TS26: adrenal medulla	Weak
TS26: bronchiole epithelium	Weak
TS26: cerebellum	Weak
TS26: corpus striatum	Weak
TS26: dermis	Weak
TS26: epidermis	Weak
TS26: hair follicle	Weak
TS26: hippocampus	Weak
TS26: inferior colliculus	Weak
TS26: lens	Weak
TS26: pons	Weak
TS26: stomach epithelium	Weak
TS26: superior colliculus	Weak
TS26: lung	Weak	Regionally restricted	Expression is in the adventitia.
TS26: liver	Weak	Single cells	Expression is in unidentified cells.
TS26: thymus	Weak	Single cells	Expression is in unidentified cells.
TS26: neocortex	Absent

Specimen Table 1 Adult: postnatal week 10; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

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Structure	Level	Pattern	Note
TS28: laryngeal cartilage	Strong
TS28: peripheral nerve	Strong
TS28: seminiferous tubule	Strong
TS28: trachea cartilage	Strong
TS28: tunica media	Strong
TS28: detrusor muscle of bladder	Moderate
TS28: heart atrium	Moderate
TS28: heart valve	Moderate
TS28: heart ventricle	Moderate
TS28: intestine muscularis	Moderate
TS28: larynx muscle	Moderate
TS28: ovary follicle	Moderate
TS28: ovary theca	Moderate
TS28: trachea smooth muscle	Moderate
TS28: uterus stroma	Moderate
TS28: lung	Moderate	Regionally restricted	Expression is in the muscularis.
TS28: esophagus muscularis	Weak
TS28: glomerular tuft	Weak
TS28: larynx submucosa	Weak
TS28: prostate gland	Weak
TS28: renal capsule	Weak
TS28: renal medulla	Weak
TS28: seminal vesicle	Weak
TS28: skeletal muscle tissue	Weak
TS28: trachea submucosa	Weak

Specimen not shown E14.0: embryonic day 14.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

)

Structure	Level	Pattern	Note
TS22: alimentary system smooth muscle	Strong
TS22: bone	Strong
TS22: cartilage	Strong
TS22: skeletal muscle tissue	Strong
TS22: smooth muscle tissue	Strong	Regionally restricted	Expression is in smooth muscle of the respiratory tracts.
TS22: blood vessel smooth muscle	Strong	Regionally restricted	Expression is in large vessels.

Specimen not shown E19: embryonic day 19.0; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS26: lens epithelium	Absent

Specimen not shown Adult: postnatal week 10; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

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Structure	Level	Pattern	Note
TS28: peripheral nerve	Strong	Regionally restricted	Expression is in small periphereal nerves, weak in large nerves.
TS28: bladder wall	Weak
TS28: large intestine wall	Weak
TS28: skeletal muscle tissue	Weak
TS28: small intestine wall	Weak
TS28: adrenal gland	Weak	Regionally restricted	Expression is in the capsule.
TS28: alveolar system	Absent
TS28: liver	Absent
TS28: lung epithelium	Absent
TS28: pancreas	Absent
TS28: spleen	Absent

Specimen not shown Adult female: postnatal week 10; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS28: endometrium	Absent

Specimen not shown Adult male: postnatal week 10; Rhobtb3^{tm1a(KOMP)Wtsi}/Rhobtb3^{tm1a(KOMP)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS28: prostate gland	Weak
TS28: seminal vesicle	Weak

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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