Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Nalcnem1Iiis
Name:	sodium leak channel, non-selective; endonuclease-mediated mutation 1, Masashi Yanagisawa and Hiromasa Funato
MGI ID:	MGI:5806546
Synonyms:	CRISPR NalcnDrl, Nalcnem1Staka
Gene:	Nalcn  Location: Chr14:123514046-123864556 bp, - strand  Genetic Position: Chr14, 66.04 cM
Alliance:	Nalcnem1Iiis page

Strain of Origin:

C57BL/6J

Allele Type:    Endonuclease-mediated (Not Specified) Mutation:    Single point mutation   Mutation details: CRISPR/Cas technology introduced A to T substitution that results in an amino acid substitution at the 315th residue from asparagine to lysine (N315K) replicating NalcnDrl. (J:236598)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Nalcn Mutation:	116 strains or lines available

Original:	J:236598 Funato H, et al., Forward-genetics analysis of sleep in randomly mutagenized mice. Nature. 2016 Nov 17;539(7629):378-383
All:	1 reference(s)