Tg(Nos1-COP4*H134R/YFP)3Gjau
Transgene Detail
|
|
| Symbol: |
Tg(Nos1-COP4*H134R/YFP)3Gjau |
| Name: |
transgene insertion 3, George Augustine |
| MGI ID: |
MGI:5805549 |
| Synonyms: |
nNOS-hChR2(H134R)-YFP |
| Transgene: |
Tg(Nos1-COP4*H134R/YFP)3Gjau Location: unknown
|
| Alliance: |
Tg(Nos1-COP4*H134R/YFP)3Gjau page
|
|
|
|
| Transgene Type: |
|
Transgenic (Reporter) |
| Mutation: |
|
Insertion
|
| |
|
Mutation details: The trangene cassette was generated by inserting the reporter cassette downstream of the translation initiation sequence in BAC RP24-164C18. The mouse promoter drives molecular layer interneuron-specific expression of the mammalian codon-optimized Chlamydomonas reinhardtii-derived channel rhodopsin-2 that was modified to harbor a gain-of-function H134R substitution (hChR2-H134R) fused in-frame with a yellow fluorescent protein (YFP) and followed by a bovin growth hormon 3'UTR. Line 3 was generated.
(J:236224)
|
|
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
|
| Original: |
J:236224 Kim J, et al., Optogenetic mapping of cerebellar inhibitory circuitry reveals spatially biased coordination of interneurons via electrical synapses. Cell Rep. 2014 Jun 12;7(5):1601-13 |
| All: |
4 reference(s) |
|