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Gene Expression Data
Assay Details
Assay
Reference: J:154075 Weatherbee SD, et al., A mouse model for Meckel syndrome reveals Mks1 is required for ciliogenesis and Hedgehog signaling. Hum Mol Genet. 2009 Dec 1;18(23):4565-75
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5805388
Gene symbol: Arl13b
Gene name: ADP-ribosylation factor-like 13B
Antibody: anti-Arl13b
Results
Specimen 4a: embryonic day 11.5 (more )
Note: Double labeled: green - Arl13b; red - gamma-tubulin.
Structure Level Pattern Image Note
TS19: hindlimb bud mesenchyme Present Regionally restricted 4a Expression is in cilia.

Specimen 4b: embryonic day 11.5; Mks1krc/Mks1krc (more )
Note: Double labeled: green - Arl13b; red - gamma-tubulin.
Structure Level Pattern Image Note
TS19: hindlimb bud mesenchyme Weak Regionally restricted 4b The number of cilia is reduced in this mutant.

Specimen 4c: embryonic day 18.5 (more )
Note: Double labeled: green - Arl13b; purple - F-actin.
Structure Level Pattern Image Note
TS26: renal tubule Present Regionally restricted 4c Expression is in cilia on the apical surface of kidney tubules.

Specimen 4d: embryonic day 18.5; Mks1krc/Mks1krc (more )
Note: Double labeled: green - Arl13b; purple - F-actin.
Structure Level Pattern Image Note
TS26: renal tubule Weak Regionally restricted 4d The number of cilia is reduced in this mutant.

Specimen 4e: embryonic day 18.5 (more )
Note: Double labeled: green - Arl13b; purple - F-actin.
Structure Level Pattern Image Note
TS26: lateral ventricle Present Regionally restricted 4e Expression is in cilia on the apical surface.

Specimen 4f: embryonic day 18.5; Mks1krc/Mks1krc (more )
Note: Double labeled: green - Arl13b; purple - F-actin.
Structure Level Pattern Image Note
TS26: lateral ventricle Weak Regionally restricted 4f The number of cilia is reduced in this mutant.

Specimen 4i: embryonic day 12.5 (more )
Note: Double labeled: green - Arl13b; red - gamma-tubulin.
Structure Level Pattern Image Note
TS20: lung epithelium Present Regionally restricted 4i Expression is in cilia.

Specimen 4j: embryonic day 12.5; Mks1krc/Mks1krc (more )
Note: Double labeled: green - Arl13b; red - gamma-tubulin.
Structure Level Pattern Image Note
TS20: lung epithelium Present Regionally restricted 4j The number of cilia is reduced in this mutant.

Specimen 4k: embryonic day 11.5 (more )
Note: Double labeled: green - Arl13b; red - gamma-tubulin.
Structure Level Pattern Image Note
TS19: neural tube Present Regionally restricted 4k Expression is in cilia.

Specimen 4l: embryonic day 11.5; Mks1krc/Mks1krc (more )
Note: Double labeled: green - Arl13b; red - gamma-tubulin.
Structure Level Pattern Image Note
TS19: neural tube Present 4l The number of cilia is reduced in this mutant.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory