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Gene Expression Data
Assay Details
Assay
Reference: J:85108 Wong JC, et al., Targeted disruption of exons 1 to 6 of the Fanconi Anemia group A gene leads to growth retardation, strain-specific microphthalmia, meiotic defects and primordial germ cell hypoplasia. Hum Mol Genet. 2003 Aug 15;12(16):2063-76
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5805296
Gene symbol: Mlh1
Gene name: mutL homolog 1
Antibody: anti-MLH1
Detection system: Secondary antibody
Assay notes: This assay is a staining of meiotic chromosomes.
Results
Specimen 6H: postnatal week 3; Fancatm1Wong/Fancatm1Wong (more )
Note: Double labeled: red - Mlh1; green - Sycp3 (assay MGI:5805288).
Structure Level Pattern Image Note
TS28: spermatocyte Present 6H Localized on meiotic chromosomes at discrete foci representing late recombination nodules. No abnormality was detected.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory