Gene Expression Data
Assay Details
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Assay
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Reference:
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J:85108
Wong JC, et al., Targeted disruption of exons 1 to 6 of the Fanconi Anemia group A gene leads to growth retardation, strain-specific microphthalmia, meiotic defects and primordial germ cell hypoplasia. Hum Mol Genet. 2003 Aug 15;12(16):2063-76
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:5805244
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Gene symbol:
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Pcna
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Gene name:
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proliferating cell nuclear antigen
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Antibody:
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PC10
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Detection system:
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Biotinylated secondary antibody/[Strept]avidin
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Results
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Specimen
6A:
(close  )
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Genetic Background:
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involves: 129S6/SvEvTac
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Mutant Allele(s):
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Fancatm1.1Wong/Fanca+
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Age:
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postnatal week 10
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Sex:
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Male
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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Specimen
6B:
(close )
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Genetic Background:
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involves: 129S6/SvEvTac
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Mutant Allele(s):
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Fancatm1.1Wong/Fancatm1.1Wong
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Age:
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postnatal week 10
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Sex:
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Male
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: spermatocyte |
Present |
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6B
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Expresse in most of the cells. Fewer proliferating cells per tubule, due to the depletion of spermatogonia and spermatocytes, despite a relatively normal number of spermatids.
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| TS28: spermatogonium |
Present |
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6B
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Expresse in most of the cells. Fewer proliferating cells per tubule, due to the depletion of spermatogonia and spermatocytes, despite a relatively normal number of spermatids.
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Analysis Tools
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