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Gene Expression Data
Assay Details
Assay
Reference: J:234183 Morita T, et al., An in situ hybridization study of Hyaluronan synthase (Has) mRNA in developing mouse molar and incisor tooth germs. Gene Expr Patterns. 2016 May;21(1):28-40
Assay type: RNA in situ
MGI Accession ID: MGI:5804794
Gene symbol: Has2
Gene name: hyaluronan synthase 2
Probe: Has2 cDNA3
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 2b: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: oral region mesenchyme Weak Regionally restricted 2b Diffuse expression in the mesenchyme underlying the dental placode.
Specimen 2e: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: oral region mesenchyme Very strong Regionally restricted 2e Expression is in the mesenchyme surrounding the tooth bud.
Specimen 2h: embryonic day 13.0 (more )
Note: Bud stage tooth.
Structure Level Pattern Image Note
TS21: oral region mesenchyme Present Regionally restricted 2h Expression is in the mesenchyme surrounding the tooth bud on the lingual side.
Specimen 2k: embryonic day 14.0 (more )
Note: Early cap stage tooth.
Structure Level Pattern Image Note
TS22: oral region mesenchyme Weak Regionally restricted 2k Expression is in the mesenchyme surrounding the tooth germ.
TS22: dental sac Weak 2k
TS22: molar dental papilla Weak 2k
Specimen 3b: embryonic day 15.0 (more )
Note: Late cap stage tooth.
Structure Level Pattern Image Note
TS23: oral region mesenchyme Weak Regionally restricted 3b Expression is in the mesenchyme surrounding the tooth germ.
TS23: molar dental papilla Weak 3b
TS23: dental sac Absent 3b
Specimen 3e: embryonic day 16.0 (more )
Note: Early bell stage tooth.
Structure Level Pattern Image Note
TS24: molar dental papilla Weak 3e
TS24: molar mesenchyme Weak Regionally restricted 3e Expression is in the mesenchyme surrounding the dental papilla.
Specimen 3h: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: molar dental papilla Present 3h
TS26: molar mesenchyme Present Regionally restricted 3h Expression is in the mesenchyme surrounding the dental papilla.
Specimen 5b: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: incisor epithelium Weak 5b
TS21: incisor mesenchyme Weak 5b
Specimen 5e: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: incisor dental papilla Weak 5e
Specimen 5h: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: incisor dental papilla Weak Regionally restricted 5h Expression is adjacent to the labial apical bud.
Specimen not shown E18: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: incisor Absent
Specimen not shown P4: postnatal day 4 (more )
Structure Level Pattern Image Note
TS28: molar Absent
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory