Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Vim-cre/ERT2)#Rshw
Name:	transgene insertion, Robert F Schwabe
MGI ID:	MGI:5804689
Synonyms:	Vim-CreER
Transgene:	Tg(Vim-cre/ERT2)#Rshw  Location: unknown
Alliance:	Tg(Vim-cre/ERT2)#Rshw page

Strain of Origin:

(CBA x C57BL/6J)F1

Transgene Type:    Transgenic (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Tg(Vim-cre/ERT2)#Rshw expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note Not Specified Vim   Mutation details: A cre/ERT2 cassette was inserted at the ATG codon in exon 1 of the Vim gene in the BAC by recombineering methods. The neo cassette was removed by flippase, and the modified BAC construct was injected into fertilized CBA x C57BL/6J oocytes. One of three founders was crossed to reporter mice for analyses. One line shows strong cre-recombinase expression induction after tamoxifen injection, however specific line number(s) used for the experiments are not given. (J:231716)

Activity:	Tissue activity of this recombinase allele
Driver:	Vim (species not specified) Summary of all recombinase alleles driven by Vim.

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:231716 Troeger JS, et al., Deactivation of hepatic stellate cells during liver fibrosis resolution in mice. Gastroenterology. 2012 Oct;143(4):1073-83.e22
All:	3 reference(s)