Summary | Mutation origin | Mutation description | Expression | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Npr3em1(cre/ERT2)Bzsh
Name:	natriuretic peptide receptor 3; endonuclease-mediated mutation 1, Bin Zhou
MGI ID:	MGI:5804184
Synonyms:	Npr3-creER, Npr3tm1.1(cre/ERT2)Bz, Npr3tm1.1(cre/ERT2)Bzsh
Gene:	Npr3  Location: Chr15:11839982-11907287 bp, - strand  Genetic Position: Chr15, 5.83 cM
Alliance:	Npr3em1(cre/ERT2)Bzsh page

Strain of Origin:

Not Specified

Allele Type:    Endonuclease-mediated (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Npr3em1(cre/ERT2)Bzsh expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Npr3 (MGI:97373)   Mutation details: Using the CRISPR/Cas9 technology, a cDNA encoding cre/ERT2 followed by the Woodchuck Post-transcriptional regulatory element and a polyadenylation sequence was inserted in frame with the translational start codon of the Npr3 gene. (J:231966)

Activity:	Tissue activity of this recombinase allele
Driver:	Npr3 (mouse) Summary of all recombinase alleles driven by Npr3. Comparative matrix view of recombinase activities Alliance mouse Npr3 gene page

In Mice Carrying this Mutation:

58 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Npr3 Mutation:	47 strains or lines available

Original:	J:231966 Zhang H, et al., Genetic lineage tracing identifies endocardial origin of liver vasculature. Nat Genet. 2016 May;48(5):537-43
All:	8 reference(s)