Summary | Mutation origin | Mutation description | Expression | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Nfatc1em3(dre)Bzsh
Name:	nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1; endonuclease-mediated mutation 3, Bin Zhou
MGI ID:	MGI:5804102
Synonyms:	Nfatc1-Dre, Nfatc1tm3.1(dreo)Bz
Gene:	Nfatc1  Location: Chr18:80649420-80756286 bp, - strand  Genetic Position: Chr18, 53.66 cM, cytoband E4
Alliance:	Nfatc1em3(dre)Bzsh page

Strain of Origin:

Not Specified

Allele Type:    Endonuclease-mediated (Recombinase) Mutation:    Insertion   Nfatc1em3(dre)Bzsh expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Nfatc1 (MGI:102469)   Mutation details: The line was generated by inserting the 2A peptide sequence derived from porcine teschovirus-1 followed by the cDNA encoding Dre recombinase and polyadenylation sequence into the exon 9 of Nfatc1 by homologous recombination using the CRISPR/Cas9 technology. (J:236001)

Activity:	Tissue activity of this recombinase allele
Driver:	Nfatc1 (mouse) Summary of all recombinase alleles driven by Nfatc1. Comparative matrix view of recombinase activities Alliance mouse Nfatc1 gene page

In Mice Carrying this Mutation:

38 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nfatc1 Mutation:	47 strains or lines available

Original:	J:236001 Zhang H, et al., Endocardium Contributes to Cardiac Fat. Circ Res. 2016 Jan 22;118(2):254-65
All:	5 reference(s)