Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Sox2tm1.1(cre/ERT2)Kinz
Name:	SRY (sex determining region Y)-box 2; targeted mutation 1.1, Bernd Kinzel
MGI ID:	MGI:5804019
Synonyms:	Sox2-IRES-CreERT2
Gene:	Sox2  Location: Chr3:34704554-34706610 bp, + strand  Genetic Position: Chr3, 16.93 cM, cytoband A2-B
Alliance:	Sox2tm1.1(cre/ERT2)Kinz page

Germline Transmission:	Earliest citation of germline transmission: J:234789
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6

Allele Type:    Targeted (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Sox2tm1.1(cre/ERT2)Kinz expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Sox2 (MGI:98364)   Mutation details: An IRES-cre/ERT2 cassette followed by an rox-flanked neo selection cassette was inserted into the 3' UTR by homologous recombination. Mice were crossed to Dre-expressing mice to delete the rox-flanked neo cassette. (J:234789)

Activity:	Tissue activity of this recombinase allele
Driver:	Sox2 (mouse) Summary of all recombinase alleles driven by Sox2. Alliance mouse Sox2 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sox2 Mutation:	56 strains or lines available

Original:	J:234789 Riccardi S, et al., MiR-210 promotes sensory hair cell formation in the organ of corti. BMC Genomics. 2016;17:309
All:	1 reference(s)