Gene Expression Data
Assay Details
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Assay
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Reference:
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J:31646
Steel KP, et al., TRP-2/DT, a new early melanoblast marker, shows that steel growth factor (c-kit ligand) is a survival factor. Development. 1992 Aug;115(4):1111-9
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:5803803
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Gene symbol:
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Dct
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Gene name:
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dopachrome tautomerase
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Probe:
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clone p5A7
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Probe preparation:
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Antisense labelled with S35 RNA
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Visualized with:
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Autoradiography
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Results
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Specimen
2A:
embryonic day 9.5
(more  )
Specimen
2A:
(close  )
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Genetic Background:
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CBA/Ca
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: optic vesicle |
Present |
Regionally restricted |
2A
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Expressed in the presumptive pigmented retinal epithelium.
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Specimen
2B:
embryonic day 10.0
(more )
Specimen
2B:
(close )
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Genetic Background:
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CBA/Ca
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Age:
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embryonic day 10.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS16: optic cup |
Present |
Regionally restricted |
2B
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Expressed in the presumptive pigmented retinal epithelium.
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Specimen
2D:
embryonic day 11.5
(more )
Specimen
2D:
(close )
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Genetic Background:
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CBA/Ca
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
2F:
embryonic day 19.5
(more )
Specimen
2F:
(close )
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Genetic Background:
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CBA/Ca
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Age:
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embryonic day 19.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: Harderian gland |
Present |
Regionally restricted |
2F
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Expressed in migratory melanocytes identified by their pigmented dendrites.
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Specimen
3A:
embryonic day 10.0
(more )
Specimen
3A:
(close )
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Genetic Background:
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CBA/Ca
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Age:
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embryonic day 10.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS16: inner ear mesenchyme |
Present |
Regionally restricted |
3A
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Expressed in migratory melanocytes in mesenchyme caudal to otocyst.
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Specimen
3B:
embryonic day 10.0
(more )
Specimen
3B:
(close )
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Genetic Background:
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CBA/Ca
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Age:
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embryonic day 10.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS16: inner ear mesenchyme |
Present |
Regionally restricted |
3B
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Expressed in melanoblasts in mesenchyme ventral to otocyst.
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Specimen
3C:
embryonic day 11.5
(more )
Specimen
3C:
(close )
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Genetic Background:
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CBA/Ca
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: inner ear mesenchyme |
Present |
Regionally restricted |
3C
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Expressed melanoblasts distributed widely in the mesenchyme around the otic vesicle.
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Specimen
3D:
embryonic day 14.5
(more )
Specimen
3D:
(close )
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Genetic Background:
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CBA/Ca
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: inner ear mesenchyme |
Present |
Regionally restricted |
3D
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Expressed in melanoblasts localised mainly to the mesenchyme above the cochlear duct.
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Specimen
3F:
embryonic day 15.5
(more )
Specimen
3F:
(close )
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Genetic Background:
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CBA/Ca
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: inner ear mesenchyme |
Present |
Regionally restricted |
3F
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Expressed in melanoblasts localised to the region of the cochlear duct that will develop into the stria vascularis.
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Specimen
3G:
embryonic day 16.5
(more )
Specimen
3G:
(close )
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Genetic Background:
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CBA/Ca
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: inner ear mesenchyme |
Present |
Regionally restricted |
3G
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Expressed in melanocytes becoming incorporated into the epithelium of the stria vascularis, particularly in the basal turn of the cochlea, which is more advanced in development than the apical turns.
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Specimen
4A:
embryonic day 13.5
(more )
Specimen
4A:
(close )
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Genetic Background:
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CBA/Ca
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: inner ear mesenchyme |
Present |
Regionally restricted |
4A
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Expressed in melanoblasts in mesenchyme ventral to otocyst.
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Specimen
4C:
embryonic day 13.5
(more )
Specimen
4C:
(close )
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Genetic Background:
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CBA/Ca
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: telencephalon |
Present |
Regionally restricted |
4C
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Expressed in the inner layer of the neuroepithelium.
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Specimen
4E:
embryonic day 12.5
(more )
Specimen
4E:
(close )
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Genetic Background:
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CBA/Ca
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: telencephalon |
Present |
Regionally restricted |
4E
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Expressed in the frontal and medial regions.
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Specimen
5A:
embryonic day 12.0
(more )
Specimen
5A:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 12.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: telencephalon |
Present |
Regionally restricted |
5A
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Expressed in restricted region in the whole thickness of the neurectoderm.
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Specimen
5B:
(close )
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Genetic Background:
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Not Specified
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Mutant Allele(s):
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KitlSl-d/KitlSl-d
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Age:
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embryonic day 12.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: telencephalon |
Present |
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5B
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Expressed in normal pattern as in the wild-type.
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Specimen
5C:
(close )
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Genetic Background:
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Not Specified
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Mutant Allele(s):
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KitlSl-d/KitlSl-d
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Age:
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embryonic day 14.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
5D:
embryonic day 14.0
(more )
Specimen
5D:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 14.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
5E:
(close )
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Genetic Background:
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Not Specified
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Mutant Allele(s):
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KitlSl-d/KitlSl-d
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Age:
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embryonic day 14.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
5F:
(close )
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Genetic Background:
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Not Specified
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Mutant Allele(s):
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KitlSl-d/KitlSl-d
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Age:
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embryonic day 12.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
6A:
embryonic day 11.0
(more )
Specimen
6A:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 11.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS18: inner ear mesenchyme |
Present |
Clusters |
6A
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Expressed in melanocytes in mesenchyme caudal to otic vesicle around anterior cardinal vein.
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Specimen
6B:
(close )
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Genetic Background:
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Not Specified
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Mutant Allele(s):
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KitlSl-d/KitlSl-d
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Age:
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embryonic day 11.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS18: inner ear mesenchyme |
Present |
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6B
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Expressed in melanocytes in mesenchyme caudal to otic vesicle around anterior cardinal vein, similar as in the wild-type.
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Specimen
6C:
embryonic day 11.0
(more )
Specimen
6C:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 11.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS18: inner ear mesenchyme |
Present |
Clusters |
6C
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Expressed in melanoblasts around the developing cochlear duct.
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Specimen
6D:
(close )
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Genetic Background:
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Not Specified
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Mutant Allele(s):
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KitlSl-d/KitlSl-d
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Age:
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embryonic day 11.0
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Sex:
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Not Specified
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Type:
|
section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS18: inner ear mesenchyme |
Present |
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6D
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Fewer positive cells at this location than in controls, and rarely appear close to the cochlear duct.
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Specimen
6E:
embryonic day 12.0
(more )
Specimen
6E:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 12.0
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Sex:
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Not Specified
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Type:
|
section
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Fixation:
|
4% Paraformaldehyde
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Embedding:
|
Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: inner ear mesenchyme |
Present |
Regionally restricted |
6E
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Expressed in melanoblasts around the developing cochlea.
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Specimen
6F:
(close )
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Genetic Background:
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Not Specified
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Mutant Allele(s):
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KitlSl-d/KitlSl-d
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Age:
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embryonic day 12.0
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Sex:
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Not Specified
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Type:
|
section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
not shown:
embryonic day 12.5
(more )
Note: Camera lucida drawing was shown in 4F.
Specimen
not shown:
(close )
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Genetic Background:
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CBA/Ca
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Age:
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embryonic day 12.5
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Sex:
|
Not Specified
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Type:
|
section
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Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
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|
Note:
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Camera lucida drawing was shown in 4F.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: telencephalon |
Strong |
Regionally restricted |
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Expressed in the frontal and medial regions.
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Specimen
not shown:
postnatal newborn
(more )
Specimen
not shown:
(close )
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Genetic Background:
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CBA/Ca
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Age:
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postnatal newborn
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: hair follicle |
Strong |
Regionally restricted |
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Expressed in melanocytes (melanin-containing cells).
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| TS27: mouse |
Strong |
Regionally restricted |
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Expressed in melanocytes (melanin-containing cells).
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| TS27: skin |
Strong |
Regionally restricted |
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Expressed in melanocytes (melanin-containing cells).
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Specimen
not shown:
embryonic day 10.0
(more )
Note: Summarized in Table 1.
Specimen
not shown:
(close )
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Genetic Background:
|
CBA/Ca
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Age:
|
embryonic day 10.0
|
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Sex:
|
Not Specified
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Type:
|
section
|
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Fixation:
|
4% Paraformaldehyde
|
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Embedding:
|
Paraffin
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|
Note:
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Summarized in Table 1.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS16: embryo mesenchyme |
Present |
Regionally restricted |
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Expressed in migratory melanoblasts.
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Specimen
not shown:
embryonic day 10.5
(more )
Note: Summarized in Table 1.
Specimen
not shown:
(close )
|
Genetic Background:
|
CBA/Ca
|
|
Age:
|
embryonic day 10.5
|
|
Sex:
|
Not Specified
|
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Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
|
Note:
|
Summarized in Table 1.
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Analysis Tools