Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Xcr1tm4(cre)Ksho
Name:	chemokine (C motif) receptor 1; targeted mutation 4, Tsuneyasu Kaisho
MGI ID:	MGI:5803711
Synonyms:	Xcr1cre
Gene:	Xcr1  Location: Chr9:123681380-123691094 bp, - strand  Genetic Position: Chr9, 74.71 cM, cytoband F4
Alliance:	Xcr1tm4(cre)Ksho page

Germline Transmission:	Earliest citation of germline transmission: J:235786
Parent Cell Line:	Bruce 4 (ES Cell)
Strain of Origin:	B6.Cg-Thy1a

Allele Type:    Targeted (Null/knockout, Recombinase) Mutations:    Insertion, Intragenic deletion   Xcr1tm4(cre)Ksho expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Xcr1 (MGI:1346338)     A cre recombinase gene and a FRT-flanked neomycin resistance cassette replaced the coding sequence. (J:235786)

Activity:	Tissue activity of this recombinase allele
Driver:	Xcr1 (mouse) Summary of all recombinase alleles driven by Xcr1. Alliance mouse Xcr1 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Xcr1 Mutation:	32 strains or lines available

Original:	J:235786 Ohta T, et al., Crucial roles of XCR1-expressing dendritic cells and the XCR1-XCL1 chemokine axis in intestinal immune homeostasis. Sci Rep. 2016 Mar 23;6:23505
All:	4 reference(s)