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Gene Expression Data
Assay Details
Assay
Reference: J:72525 Schubert FR, et al., Early mesodermal phenotypes in splotch suggest a role for Pax3 in the formation of epithelial somites. Dev Dyn. 2001 Nov;222(3):506-21
Assay type: RNA in situ
MGI Accession ID: MGI:5803700
Gene symbol: Pax1
Gene name: paired box 1
Results
Specimen 4A: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: sclerotome Strong Regionally restricted 4A Expression was strong in the caudal halves of the lumbar sclerotomes, as well as in the centers of the sclerotomes.

Specimen 4B: embryonic day 12.0; Dll3pu/Dll3pu (more )
Structure Level Pattern Image Note
TS20: sclerotome Strong Regionally restricted 4B Signals were fused. There was an irregular array of elevated signals.

Specimen 4C: embryonic day 12.0; rh/rh (more )
Structure Level Pattern Image Note
TS20: sclerotome Present Regionally restricted 4C Signal was fused.

Specimen 4D: embryonic day 12.0; Pax3Sp/Pax3Sp (more )
Structure Level Pattern Image Note
TS20: sclerotome Present Regionally restricted 4D The ventromedial to dorsolateral extent of expression was normal. However, the three sclerotomes indicated display irregular and fused signals with altered rostrocaudal pattern. Strong signal in the rostral sclerotome halves, lateral to the negative spots. In the caudal sclerotome halves and ventromedially levels of expression are reduced.

Specimen 4E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: sclerotome Present Regionally restricted 4E Expression was highest in the caudal sclerotome halves.
TS17: spinal nerve Absent 4E Expression was negative in the spinal nerve in the lateral territory of the rostral sclerotome half.

Specimen 4F: embryonic day 10.5; Dll3pu/Dll3pu (more )
Structure Level Pattern Image Note
TS17: sclerotome Present Regionally restricted 4F Signals were fused. Lighter and darker staining appears at irregular intervals.

Specimen 4G: embryonic day 10.5; rh/rh (more )
Structure Level Pattern Image Note
TS17: sclerotome Present Regionally restricted 4G Signals were fused with ill-defined rostrocaudal pattern.

Specimen 4H: embryonic day 10.5; Pax3Sp/Pax3Sp (more )
Structure Level Pattern Image Note
TS17: sclerotome Present Regionally restricted 4H The rostrocaudal pattern of expression was altered. The ventromedial to dorsolateral extent was not changed. Sclerotomes exhibited fused signals and an erroneous pattern of up-regulation.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory