About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:135516 Wansbury O, et al., Dynamic expression of Erbb pathway members during early mammary gland morphogenesis. J Invest Dermatol. 2008 Apr;128(4):1009-21
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5800293
Gene symbol: Egfr
Gene name: epidermal growth factor receptor
Antibody: anti-EGFR
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Assay notes: Fixative was either: 4% paraformaldehyde, formalin, or Carnoy's fixative.
Results
Specimen 2f: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: mammary placode Present 2f
TS19: surface ectoderm Present 2f
Specimen 2g: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: mammary bud Weak 2g
TS20: skin Weak Regionally restricted 2g Expression is in the epithelium adjacent to the mammary bud.
Specimen 2i: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: mammary bud Weak 2i
TS21: skin Weak Regionally restricted 2i Expression is in the epithelium adjacent to the mammary bud.
TS21: trunk mesenchyme Present Regionally restricted 2i Expression is in mesenchyme directly adjacent to the mammary mesenchyme on both the dorsal and ventral edges of the mammary bud.
Specimen 2j: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: epidermis Present 2j
TS22: mammary gland primordium epithelium Present 2j
TS22: dermis Weak Regionally restricted 2j Expression is throughout the dermal mesenchyme except for the mammary mesenchyme.
TS22: mammary mesenchyme Absent 2j
Specimen S2: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: mammary bud Present S2_Erbb1
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory