About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:135516 Wansbury O, et al., Dynamic expression of Erbb pathway members during early mammary gland morphogenesis. J Invest Dermatol. 2008 Apr;128(4):1009-21
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5800287
Gene symbol: Nrg1
Gene name: neuregulin 1
Antibody: anti-Nrg1b (C-20)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Assay notes: Fixative was either: 4% paraformaldehyde, formalin, or Carnoy's fixative.
Results
Specimen 6f: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: mammary placode Present 6f
TS19: surface ectoderm Present Regionally restricted 6f Expression is in the epithelium adjacent to the placode.

Specimen 6h: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: mammary bud Present 6h
TS20: epidermis Present Regionally restricted 6h Expression is in the epithelium adjacent to the mammary bud.

Specimen 6j: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: epidermis Present Regionally restricted 6j Expression is in the epithelium adjacent to the mammary bud.
TS21: mammary gland primordium epithelium Weak 6j
TS21: mammary mesenchyme Absent 6j

Specimen 6l: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: epidermis Moderate 6l
TS22: mammary gland primordium Weak 6l
TS22: mammary gland primordium epithelium Weak 6l
TS22: mammary mesenchyme Absent 6l


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/07/2024
MGI 6.23
The Jackson Laboratory