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Gene Expression Data
Assay Details
Assay
Reference: J:135516 Wansbury O, et al., Dynamic expression of Erbb pathway members during early mammary gland morphogenesis. J Invest Dermatol. 2008 Apr;128(4):1009-21
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5800281
Gene symbol: Erbb4
Gene name: erb-b2 receptor tyrosine kinase 4
Antibody: anti-Erbb4 (C-18): sc-283
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Assay notes: Fixative was either: 4% paraformaldehyde, formalin, or Carnoy's fixative.
Results
Specimen 5g: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: mammary placode Present 5g , 5h
TS20: skin Present Regionally restricted 5h , 5g Expression is in the epithelium adjacent to the mammary placode.

Specimen 5i: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: mammary bud Present 5i
TS20: epidermis Present Regionally restricted 5i Expression is in the epithelium adjacent to the mammary bud.

Specimen 5j: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: mammary bud Present 5j
TS21: epidermis Present Regionally restricted 5j Expression is in the epithelium adjacent to the mammary bud.

Specimen 5k: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: epidermis Moderate 5k
TS22: connective tissue Moderate Regionally restricted 5k Expression is at the site of the future fat pad.
TS22: mammary gland primordium epithelium Trace 5k

Specimen S2: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: mammary bud Present S2_Erbb4


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/30/2025
MGI 6.24
The Jackson Laboratory