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Gene Expression Data
Assay Details
Assay
Reference: J:135516 Wansbury O, et al., Dynamic expression of Erbb pathway members during early mammary gland morphogenesis. J Invest Dermatol. 2008 Apr;128(4):1009-21
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5800279
Gene symbol: Erbb2
Gene name: erb-b2 receptor tyrosine kinase 2
Antibody: anti-Erbb2 (C18; sc-284)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Assay notes: Fixative was either: 4% paraformaldehyde, formalin, or Carnoy's fixative.
Results
Specimen 3c: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: dorsal root ganglion Present 3c
TS18: embryo mesenchyme Present 3c
TS18: heart atrium Present 3c
TS18: primitive ventricle Present 3c
TS18: somite Present 3c
TS18: urogenital ridge Present 3c
TS18: neural tube lateral wall Present Regionally restricted 3c Expression is in motorneurons.

Specimen 3d: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: mammary bud Present 3d
TS20: epidermis Present Regionally restricted 3d Expression is in the surface epithelium adjacent to the mammary bud.

Specimen 3e: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: epidermis Present Regionally restricted 3e Expression is in the basal layer.
TS21: mammary gland primordium epithelium Present Regionally restricted 3e Expression is in the basal layer.
TS21: connective tissue Present Regionally restricted 3e Expression is at the site of the future fat pad.
TS21: mammary mesenchyme Present Regionally restricted 3e Expression is in the mesenchyme in the vicinity of the future site of the fat pad.

Specimen 3f: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: epidermis Moderate Regionally restricted 3f Expression is in the surface epithelium adjacent to the mammary bud.
TS22: mammary bud Moderate 3f Moderate expression in the neck of the mammary bud and weak in the mature mammary bud.
TS22: mammary mesenchyme Present Regionally restricted 3f Expression is in the mesenchyme in the vicinity of the future site of the fat pad.
TS22: connective tissue Present Regionally restricted 3f Expression is at the site of the future fat pad.

Specimen S2: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: mammary bud Present S2_Erbb2


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory