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Igs7tm3(tetO-Optopatch3,CAG-tTA)Acoh
Targeted Allele Detail
Summary
Symbol: Igs7tm3(tetO-Optopatch3,CAG-tTA)Acoh
Name: intergenic site 7; targeted mutation 3, Adam Cohen
MGI ID: MGI:5796839
Synonyms: Ai155, FLOXed Optopatch-3
Gene: Igs7  Location: unknown  Genetic Position: Chr9, Syntenic
Alliance: Igs7tm3(tetO-Optopatch3,CAG-tTA)Acoh page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:101977
Parent Cell Line:  G4 (ES Cell)
Strain of Origin:  (129S6/SvEvTac x C57BL/6NCrl)F1
Mutation
description
Allele Type:    Targeted (Conditional ready, Inducible, Reporter)
Inducer:    doxycycline/tetracycline
Mutation:    Insertion
 
Mutation detailsThe targeting construct contains a tetO (tetracycline response element; TRE)-loxP-Stop-loxP-Optopatch3-CAG-tTA (tetracycline-controlled transactivator). Optopatch3 is a bicistronic construct that coexpresses QuasAr3-mCitrine (an enhanced archaerhodopsin-3 (Arch)-based voltage indicator) and CheRiff (a sensitive blue-shifted optogenetic actuator) (J:101977)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Igs7 Mutation:  64 strains or lines available
References
Original:  J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory