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Gene Expression Data
Assay Details
Assay
Reference: J:100495 Howard B, et al., Identification of the scaramanga gene implicates Neuregulin3 in mammary gland specification. Genes Dev. 2005 Sep 1;19(17):2078-90
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5796680
Gene symbol: Nrg3
Gene name: neuregulin 3
Antibody: Nrg3 antibody
Detection system: horseradish peroxidase
Assay notes: Authors describe 3 Nrg3 antibodies (MGI:5796665, MGI:5796667 and MGI:5796669) but do not specify which was used in this assay.
Results
Specimen not shown 54 somites: embryonic day 12.5 (more )
Note: 54 somites
Structure Level Pattern Image Note
TS21: mammary gland primordium epithelium Present Regionally restricted Expression in epithelial cells of mammary bud 3 when the bud proper has formed.
Specimen 3J: embryonic day 12.5 (more )
Note: 54 somites
Structure Level Pattern Image Note
TS21: nervous system Present Widespread 3J Widespread neural expression.
TS21: mammary bud Present Regionally restricted 3J Expression in mammary buds 1 and 4
Specimen 3J inset 1: embryonic day 12.5 (more )
Note: 54 somites
Structure Level Pattern Image Note
TS21: mammary bud Present Regionally restricted 3J inset 1 Expression in mesenchyme adjacent to mammary epithelia. Expression in a few mammary epithelial cells.
TS21: nerve Present 3J inset 1 Expression in a nerve.
Specimen 3J inset 4: embryonic day 12.5 (more )
Note: 54 somites
Structure Level Pattern Image Note
TS21: mammary gland primordium epithelium Present Regionally restricted 3J inset 4 Expression in epithelial cells of mammary bud. Expression in epithelia adjacent to the mammary bud.
Specimen 3K: embryonic day 13.0 (more )
Note: 60 somites
Structure Level Pattern Image Note
TS22: mammary gland primordium epithelium Present Regionally restricted 3K Expression in mammary bud 4 and adjacent epithelia. By E13, expression in epithelium of all mammary buds
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/28/2024
MGI 6.13 		The Jackson Laboratory