Sumf1tm1Clear
Targeted Allele Detail
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| Symbol: |
Sumf1tm1Clear |
| Name: |
sulfatase modifying factor 1; targeted mutation 1, Andrea Ballabio |
| MGI ID: |
MGI:5796637 |
| Gene: |
Sumf1 Location: Chr6:108083989-108162543 bp, - strand Genetic Position: Chr6, 49.71 cM
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| Alliance: |
Sumf1tm1Clear page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:188481
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| Parent Cell Line: |
Bruce 4 (ES Cell)
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| Strain of Origin: |
B6.Cg-Thy1a
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| Allele Type: |
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Targeted (Conditional ready) |
| Mutation: |
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Insertion
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Mutation details: A loxP site4 was introduced upstream and a frt site-flanked neomycin resistance cassette followed by a second loxP site downstream of exon 4. Cre recombinase excision of the floxed DNA segment would result in a reading frame shift leading to a premature termination codon.
(J:188481)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Sumf1 Mutation: |
32 strains or lines available
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| Original: |
J:188481 Di Malta C, et al., Astrocyte dysfunction triggers neurodegeneration in a lysosomal storage disorder. Proc Natl Acad Sci U S A. 2012 Aug 28;109(35):E2334-42 |
| All: |
1 reference(s) |
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Analysis Tools
