Summary | Mutation origin | Mutation description | Expression | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Mafbtm1.1(cre)Kmm
Name:	MAF bZIP transcription factor B; targeted mutation 1.1, Kenneth Murphy
MGI ID:	MGI:5795905
Synonyms:	MafB-mCherry-Cre, Mafbtm1.1(mCherry,cre)Kmm
Gene:	Mafb  Location: Chr2:160205623-160208985 bp, - strand  Genetic Position: Chr2, 80.92 cM
Alliance:	Mafbtm1.1(cre)Kmm page

Germline Transmission:	Earliest citation of germline transmission: J:101977
Parent Cell Line:	JM8.N4 (ES Cell)
Strain of Origin:	C57BL/6N

Allele Type:    Targeted (Recombinase, Reporter) Mutation:    Insertion   Mafbtm1.1(cre)Kmm expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Mafb (MGI:104555)   Mutation details: A targeting construct was designed to insert a FLAG-tagged-mCherry fluorescent protein and a Cre Recombinase sequence, separated by two different viral 2A oligopeptides that mediate ribosomal skipping (P2A [from porcine teschovirus-1] and T2A [from insect Thosea asigna virus], into the coding sequence of the Mafb (v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)) gene. A frt-flanked neomycin resistance (neo) cassette was inserted 3' of the cre sequence. Resulting mice were bred to FLP1 exspressing mice to remove the neo cassette. (J:101977)

Activity:	Tissue activity of this recombinase allele
Driver:	Mafb (mouse) Summary of all recombinase alleles driven by Mafb. Alliance mouse Mafb gene page

In Mice Carrying this Mutation:

9 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mafb Mutation:	18 strains or lines available

Original:	J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:	7 reference(s)