Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Vgftm4.1Srjs
Name:	VGF nerve growth factor inducible; targeted mutation 4.1, Stephen R J Salton
MGI ID:	MGI:5793050
Synonyms:	VGFflox
Gene:	Vgf  Location: Chr5:137055246-137062205 bp, + strand  Genetic Position: Chr5, 76.13 cM
Alliance:	Vgftm4.1Srjs page

Germline Transmission:	Earliest citation of germline transmission: J:225814
Parent Cell Line:	iTL BA1 (ES Cell)
Strain of Origin:	(C57BL/6NTac x 129S6/SvEvTac)F1

Allele Type:    Targeted (Conditional ready) Mutation:    Insertion   Mutation details: A loxP site was inserted into the 5'UTR. Flp-mediated recombination removed an FRT-flanked neomycin resistance cassette with a 3' loxP site inserted into the 3' UTR. (J:225814)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Vgf Mutation:	26 strains or lines available

Original:	J:225814 Lin WJ, et al., VGF and Its C-Terminal Peptide TLQP-62 Regulate Memory Formation in Hippocampus via a BDNF-TrkB-Dependent Mechanism. J Neurosci. 2015 Jul 15;35(28):10343-56
All:	6 reference(s)