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Gene Expression Data
Assay Details
Assay
Reference: J:206928 Piper M, et al., NFIB-Mediated Repression of the Epigenetic Factor Ezh2 Regulates Cortical Development. J Neurosci. 2014 Feb 19;34(8):2921-30
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5792932
Gene symbol: Ezh2
Gene name: enhancer of zeste 2 polycomb repressive complex 2 subunit
Antibody: anti-Ezh2 (AC22; #3147)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 3A': embryonic day 14.0 (more )
Note: Double labeled: green - Ezh2; red - Nfib (assay MGI:5792931).
Structure Level Pattern Image Note
TS22: neocortex Present Regionally restricted 3A' middle , 3A' merge Expressed in the ventricular zone. Coexpressed with Nfib.

Specimen 3A": embryonic day 14.0 (more )
Note: Double labeled: green - Ezh2; red - Nfib (assay MGI:5792931).
Structure Level Pattern Image Note
TS22: hippocampus Present Regionally restricted 3A" merge , 3A" middle Expressed in the ventricular zone. Coexpressed with Nfib.

Specimen 3B': embryonic day 16.0 (more )
Note: Double labeled: green - Ezh2; red - Nfib (assay MGI:5792931).
Structure Level Pattern Image Note
TS24: neocortex Present Regionally restricted 3B' middle , 3B' merge Expressed in the ventricular zone. Coexpressed with Nfib.

Specimen 3B": embryonic day 16.0 (more )
Note: Double labeled: green - Ezh2; red - Nfib (assay MGI:5792931).
Structure Level Pattern Image Note
TS24: hippocampus ventricular layer Present 3B" middle , 3B" merge Coexpressed with Nfib.

Specimen 5A': embryonic day 16.0 (more )
Note: Double labeled: green - Ezh2; red - Pax6 (assay MGI:5792933).
Structure Level Pattern Image Note
TS24: neocortex Present Regionally restricted 5A' merge , 5A' middle Expressed in the ventricular zone.

Specimen 5A": embryonic day 16.0 (more )
Note: Double labeled: green - Ezh2; red - Pax6 (assay MGI:5792933).
Structure Level Pattern Image Note
TS24: hippocampus ventricular layer Present 5A" merge , 5A" middle

Specimen 5B': embryonic day 16.0; Nfibtm1Rmg/Nfibtm1Rmg (more )
Note: Double labeled: green - Ezh2; red - Pax6 (assay MGI:5792933).
Structure Level Pattern Image Note
TS24: neocortex Present Regionally restricted 5B' merge , 5B' middle Expressed in the ventricular zone. Significantly more positive neural progenitor cells, compared with the wild-type.

Specimen 5B": embryonic day 16.0; Nfibtm1Rmg/Nfibtm1Rmg (more )
Note: Double labeled: green - Ezh2; red - Pax6 (assay MGI:5792933).
Structure Level Pattern Image Note
TS24: hippocampus ventricular layer Present 5B" middle , 5B" merge Significantly more positive neural progenitor cells, compared with the wild-type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory