Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Il1r1tm1.1Wme
Name:	interleukin 1 receptor, type I; targeted mutation 1.1, Werner Mueller
MGI ID:	MGI:5792908
Synonyms:	Il1r1fl, Il1r1tm1.1Awai
Gene:	Il1r1  Location: Chr1:40264240-40356417 bp, + strand  Genetic Position: Chr1, 18.81 cM
Alliance:	Il1r1tm1.1Wme page

Germline Transmission:	Earliest citation of germline transmission: J:229105
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6N

Allele Type:    Targeted (Conditional ready) Mutation:    Insertion   Mutation details: An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted upstream of exon 5. An F3 flanked puromycin resistance cassette with a 3' loxP site was inserted downstream of exon 5. Flp-mediated recombination removed both selection cassettes and left exon 5 floxed. (J:229105, J:241494)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Il1r1 Mutation:	39 strains or lines available

Original:	J:229105 Bruttger J, et al., Genetic Cell Ablation Reveals Clusters of Local Self-Renewing Microglia in the Mammalian Central Nervous System. Immunity. 2015 Jul 21;43(1):92-106
All:	14 reference(s)