Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Ptchd1tm1Gfng
Name:	patched domain containing 1; targeted mutation 1, Guoping Feng
MGI ID:	MGI:5792575
Synonyms:	Ptchd1-YFP
Gene:	Ptchd1  Location: ChrX:154356451-154406810 bp, - strand  Genetic Position: ChrX, 72.38 cM
Alliance:	Ptchd1tm1Gfng page

Germline Transmission:	Earliest citation of germline transmission: J:232709
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: A targeting vector containing ATG-eYFP-STOP (bovine growth hormone poly-A tail) cassette and a FRT site flanked-NEO cassette was used to disrupt and replace exon 1 of the X linked Ptchd1 gene. (J:232709)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ptchd1 Mutation:	9 strains or lines available

Original:	J:232709 Wells MF, et al., Thalamic reticular impairment underlies attention deficit in Ptchd1(Y/-) mice. Nature. 2016 Apr 7;532(7597):58-63
All:	2 reference(s)