Gene Expression Data
Assay Details
|
Assay
|
|
Reference:
|
J:133682
Jones NC, et al., Prevention of the neurocristopathy Treacher Collins syndrome through inhibition of p53 function. Nat Med. 2008 Feb;14(2):125-33
|
|
Assay type:
|
Immunohistochemistry
|
|
MGI Accession ID:
|
MGI:5792131
|
|
Gene symbol:
|
Casp3
|
|
Gene name:
|
caspase 3
|
|
Antibody:
|
anti-caspase3 (3G2) (#9668)
|
|
Detection system:
|
Secondary antibody
|
|
Assay notes:
|
The antibody recognizes the activated form of the protein.
|
|
|
Results
|
Specimen
4a:
embryonic day 9.0-9.5
(more )
Specimen
4a:
(close )
|
Genetic Background:
|
involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 * DBA
|
|
Age:
|
embryonic day 9.0-9.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
Specimen
4b:
embryonic day 9.0-9.5; Tcof1tm1Mjd/Tcof1 +
(more )
Specimen
4b:
(close )
|
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/1
|
|
Mutant Allele(s):
|
Tcof1tm1Mjd/Tcof1+
|
|
Age:
|
embryonic day 9.0-9.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
Specimen
4c:
(close )
|
Genetic Background:
|
involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 * DBA
|
|
Mutant Allele(s):
|
Tcof1tm1Mjd/Tcof1+ Trp53tm1Brd/Trp53+
|
|
Age:
|
embryonic day 9.0-9.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
Specimen
S1a:
(close )
|
Genetic Background:
|
involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 * DBA
|
|
Mutant Allele(s):
|
Tcof1tm1Mjd/Tcof1+ Trp53tm1Brd/Trp53+
|
|
Age:
|
embryonic day 9.0
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
Specimen
S1b:
(close )
|
Genetic Background:
|
involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 * DBA
|
|
Mutant Allele(s):
|
Tcof1tm1Mjd/Tcof1+ Trp53tm1Brd/Trp53tm1Brd
|
|
Age:
|
embryonic day 9.0
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
Specimen
S1c Tcof1+/+:
embryonic day 9.0
(more )
Note: Quantification of positive cell numbers are shown in a table.
Specimen
S1c Tcof1+/+:
(close )
|
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA
|
|
Age:
|
embryonic day 9.0
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
|
Note:
|
Quantification of positive cell numbers are shown in a table.
|
Specimen
S1c Tcof1+/-:
embryonic day 9.0; Tcof1tm1Mjd/Tcof1 +
(more )
Note: Quantification of positive cell numbers are shown in a table.
Specimen
S1c Tcof1+/-:
(close )
|
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/1
|
|
Mutant Allele(s):
|
Tcof1tm1Mjd/Tcof1+
|
|
Age:
|
embryonic day 9.0
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
|
Note:
|
Quantification of positive cell numbers are shown in a table.
|
Specimen
S1c Tcof1+/-;p53+/-:
embryonic day 9.0; Tcof1tm1Mjd/Tcof1 +, Trp53tm1Brd/Trp53 +
(more )
Note: Quantification of positive cell numbers are shown in a table.
Specimen
S1c Tcof1+/-;p53+/-:
(close )
|
Genetic Background:
|
involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 * DBA
|
|
Mutant Allele(s):
|
Tcof1tm1Mjd/Tcof1+ Trp53tm1Brd/Trp53+
|
|
Age:
|
embryonic day 9.0
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
|
Note:
|
Quantification of positive cell numbers are shown in a table.
|
Specimen
S1c Tcof1+/-;p53-/-:
embryonic day 9.0; Tcof1tm1Mjd/Tcof1 +, Trp53tm1Brd/ Trp53tm1Brd
(more )
Note: Quantification of positive cell numbers are shown in a table.
Specimen
S1c Tcof1+/-;p53-/-:
(close )
|
Genetic Background:
|
involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 * DBA
|
|
Mutant Allele(s):
|
Tcof1tm1Mjd/Tcof1+ Trp53tm1Brd/Trp53tm1Brd
|
|
Age:
|
embryonic day 9.0
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
|
Note:
|
Quantification of positive cell numbers are shown in a table.
|
|