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Gene Expression Data
Assay Details
Assay
Reference: J:958 Sham MH, et al., Analysis of the murine Hox-2.7 gene: conserved alternative transcripts with differential distributions in the nervous system and the potential for shared regulatory regions. EMBO J. 1992 May;11(5):1825-36
Assay type: RNA in situ
MGI Accession ID: MGI:5791957
Gene symbol: Hoxb3
Gene name: homeobox B3
Probe: Hox2.7 exon IV (common) probe2
Probe preparation: DNA
Results
Specimen 6a,b: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: central nervous system Present Regionally restricted 6a/b Clear dorsal restriction and anterior limit of expression.
TS20: hindbrain Weak Regionally restricted 6a/b Faint domain of expression extending more anteriorly in the hindbrain.
TS20: vertebral pre-cartilage condensation Present Regionally restricted 6a/b Expression in prevertebra with anterior boundary at C1
TS20: inferior glossopharyngeal ganglion Present 6a/b
TS20: inferior vagus ganglion Present 6a/b

Specimen 6c,d: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: vertebral pre-cartilage condensation Present Regionally restricted 6c/d Expression in prevertebra with anterior boundary at C1.
TS20: thyroid gland Present Regionally restricted 6c/d Expression in mesenchyme of thyroid gland and thymus.

Specimen 6e: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future hindbrain Present Regionally restricted 6e Sharp anterior limit of expression in hindbrain which maps to the boundary between rhombomeres 4 and 5.

Specimen 6f: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: 3rd branchial arch ectoderm Present 6f Expression in surface ectoderm and mesenchymal tissues of 3rd and posterior branchial arches
TS15: 3rd branchial arch mesenchyme Present 6f Expression in surface ectoderm and mesenchymal tissues of 3rd and posterior branchial arches

Specimen 6g: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: dorsal root ganglion Present 6g

Specimen 6h: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lung Present 6h
TS20: mesonephric tubule Present 6h
TS20: metanephros Present 6h
TS20: pancreas Present 6h
TS20: stomach Present 6h

Specimen 7A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: central nervous system Present Regionally restricted 7A Anterior boundary of expression in the hindbrain.
TS20: hindbrain Present Regionally restricted 7A Additional domain of expression extending more anteriorly, up to the boundary of rhombomeres 2 and 3.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory