Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Gt(ROSA)26Sortm1(EGFP/CETN1)Sev
Name:	gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Sylvia Evans
MGI ID:	MGI:5790942
Synonyms:	ROSA-Neo-EGFP-Cetn1
Gene:	Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance:	Gt(ROSA)26Sortm1(EGFP/CETN1)Sev page

Germline Transmission:	Earliest citation of germline transmission: J:234834
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129

Allele Type:    Targeted (Conditional ready, Humanized sequence, Inserted expressed sequence, Reporter) Mutation:    Insertion   Gt(ROSA)26Sortm1(EGFP/CETN1)Sev expresses 1 gene Knock-in expresses: Organism Expressed Gene Homolog in Mouse Note human CETN1 (1068) Cetn1  (MGI:1347086) GFP fusion protein   Mutation details: A targeting vector containing a loxP-flanked PGK-NEO cassette and a triplicate SV40 polyA sequence, followed by an EGFP-Centrin 1 fusion cassette (cDNA of the human centrin 1 gene, CETN1, fused in frame, with EGFP at the N-terminus) with Bovine Growth Hormone polyA sequence, was inserted into the GT(ROSA)26Sor locus. (J:234834)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:	942 strains or lines available

Original:	J:234834 Hirai M, et al., Generation and Characterization of a Tissue-Specific Centrosome Indicator Mouse Line. Genesis. 2016 May;54(5):286-96
All:	6 reference(s)