Gene Expression Data
Assay Details
|
Assay
|
|
Reference:
|
J:165711
Mittal A, et al., Fibronectin and integrin alpha 5 play essential roles in the development of the cardiac neural crest. Mech Dev. 2010 Sep-Dec;127(9-12):472-84
|
|
Assay type:
|
Immunohistochemistry
|
|
MGI Accession ID:
|
MGI:5789192
|
|
Gene symbol:
|
Tfap2a
|
|
Gene name:
|
transcription factor AP-2, alpha
|
|
|
Results
|
Specimen
3B Control:
embryonic day 9.5
(more  )
Specimen
3B Control:
(close  )
|
Genetic Background:
|
involves: 129S2/SvPas * C57BL/6J
|
|
Age:
|
embryonic day 9.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
Specimen
3B FN-null:
(close )
|
Genetic Background:
|
involves: 129S2/SvPas * C57BL/6J
|
|
Mutant Allele(s):
|
Fn1tm1Hyn/Fn1tm1Hyn
|
|
Age:
|
embryonic day 9.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
Specimen
5C Control:
embryonic day 8.5
(more )
Note: 10-11 somite stage
Specimen
5C Control:
(close )
|
Genetic Background:
|
involves: 129S2/SvPas * C57BL/6J
|
|
Age:
|
embryonic day 8.5
|
|
Age Note:
|
Age assigned by curator based on morphological criteria supplied by authors.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
|
Note:
|
10-11 somite stage
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS13: neural crest |
Present |
Regionally restricted |
5C Control
|
Expression in cardiac neural crest progenitors in the dorsal neural tube.
|
Specimen
5C FN-null:
embryonic day 8.5; Fn1tm1Hyn/ Fn1tm1Hyn
(more )
Note: 10-11 somite stage
Specimen
5C FN-null:
(close )
|
Genetic Background:
|
involves: 129S2/SvPas * C57BL/6J
|
|
Mutant Allele(s):
|
Fn1tm1Hyn/Fn1tm1Hyn
|
|
Age:
|
embryonic day 8.5
|
|
Age Note:
|
Age assigned by curator based on morphological criteria supplied by authors.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
|
Note:
|
10-11 somite stage
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS13: neural crest |
Present |
Regionally restricted |
5C FN-null
|
Authors state the average number of cardiac progenitors was 10% lower compared with control embryos.
|
|
Analysis Tools
