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Ston1tm1.1Tmar
Targeted Allele Detail
Summary
Symbol: Ston1tm1.1Tmar
Name: stonin 1; targeted mutation 1.1, Tanja Maritzen
MGI ID: MGI:5788726
Synonyms: Stonin1-
Gene: Ston1  Location: Chr17:88905043-88955293 bp, + strand  Genetic Position: Chr17, 58.1 cM, cytoband E5
Alliance: Ston1tm1.1Tmar page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:227201
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsReplacement of the first coding exon, which comprises most of the protein-coding sequence, by a floxed neomycin-resistance cassette. The resulting chimeric males were mated with Ella-Cre deletermice to remove the neomycin-resistance cassette. (J:227201)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ston1 Mutation:  49 strains or lines available
References
Original:  J:227201 Feutlinske F, et al., Stonin1 mediates endocytosis of the proteoglycan NG2 and regulates focal adhesion dynamics and cell motility. Nat Commun. 2015;6:8535
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory