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Gene Expression Data
Assay Details
Assay
Reference: J:133600 Aoki M, et al., R-spondin2 expression in the apical ectodermal ridge is essential for outgrowth and patterning in mouse limb development. Dev Growth Differ. 2008 Feb;50(2):85-95
Assay type: RNA in situ
MGI Accession ID: MGI:5788483
Gene symbol: Lmx1b
Gene name: LIM homeobox transcription factor 1 beta
Probe: Lmx1b probe9
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen E10.5 mutant forelimb not shown: embryonic day 10.5; Rspo2tm1Hoka/Rspo2tm1Hoka (more )
Structure Level Pattern Image Note
TS17: forelimb bud apical ectodermal ridge Present

Specimen E10.5 wildtype forelimb not shown: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud apical ectodermal ridge Present

Specimen E11.5 mutant forelimb not shown: embryonic day 11.5; Rspo2tm1Hoka/Rspo2tm1Hoka (more )
Structure Level Pattern Image Note
TS19: handplate apical ectodermal ridge Present

Specimen E11.5 wildtype forelimb not shown: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: footplate apical ectodermal ridge Present

Specimen 6G: embryonic day 10.5; Rspo2tm1Hoka/Rspo2tm1Hoka (more )
Structure Level Pattern Image Note
TS17: hindlimb bud ectoderm Present Regionally restricted 6G Expression expanded toward the ventral side compared with wildtype embryos.

Specimen 6H: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: hindlimb bud ectoderm Present 6H

Specimen E11.5 mutant hindlimb not shown: embryonic day 11.5; Rspo2tm1Hoka/Rspo2tm1Hoka (more )
Structure Level Pattern Image Note
TS19: footplate apical ectodermal ridge Present

Specimen E11.5 wildtupe hindlimb: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: footplate apical ectodermal ridge Present


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory