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Tg(Ighm14-1H3)OK44Khyk
Transgene Detail
Summary
Symbol: Tg(Ighm14-1H3)OK44Khyk
Name: transgene insertion OK44, Kyoko Hayakawa
MGI ID: MGI:5784675
Synonyms: VHQ52/D/JH4-mju
Transgene: Tg(Ighm14-1H3)OK44Khyk  Location: unknown  
Alliance: Tg(Ighm14-1H3)OK44Khyk page
Transgene
origin
Strain of Origin:  FVB
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Ighm14-1H3)OK44Khyk expresses 1 gene
 
Mutation detailsThe unmutated VHQ52/D/JH4-mju rearrangement was cloned from hybridoma 14-1H3 (using PCR primers upstream of the Ighv promoter region and downstream of the Ighj4 gene segment) and inserted into an Ighm allotype genome. Line OK44 was generated. (J:232795)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:232795 Hayakawa K, et al., Loss of a chromosomal region with synteny to human 13q14 occurs in mouse chronic lymphocytic leukemia that originates from early-generated B-1 B cells. Leukemia. 2016 Jul;30(7):1510-9
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory