Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(HBB)72Gsv
Name:	transgene insertion 72, Frank Grosveld
MGI ID:	MGI:5784875
Synonyms:	hbeta-globin ln72, hb-globin ln72, Ln72
Transgene:	Tg(HBB)72Gsv  Location: unknown
Alliance:	Tg(HBB)72Gsv page

Strain of Origin:

Not Specified

Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence) Mutation:    Insertion   Tg(HBB)72Gsv expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human HBB (3043) Hbb-b1  (MGI:96021) Hbb-b2  (MGI:96022) Hbb-bh2  (MGI:96025) Hbb-bs  (MGI:5474852) Hbb-bt  (MGI:5474850)   Tg(HBB)72Gsv expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Homolog in Mouse Note human HBB (3043) Hbb-b1  (MGI:96021) Hbb-b2  (MGI:96022) Hbb-bh2  (MGI:96025) Hbb-bs  (MGI:5474852) Hbb-bt  (MGI:5474850)   Mutation details: A 70kb fragment encomapssing the entire human HBB genomic locus, including the epsilon, gamma and beta genes, was used in a construct to generate transgenic mice. Four mouse lines were created, 2, 13, 15 and 72. Line 72 contains one copy number of the inserted sequence. (J:132056)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:132056 Strouboulis J, et al., Developmental regulation of a complete 70-kb human beta-globin locus in transgenic mice. Genes Dev. 1992 Oct;6(10):1857-64
All:	4 reference(s)