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Gene Expression Data
Assay Details
Assay
Reference: J:15577 Swiatek PJ, et al., Perinatal lethality and defects in hindbrain development in mice homozygous for a targeted mutation of the zinc finger gene Krox20. Genes Dev. 1993 Nov;7(11):2071-84
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5780201
Gene symbol: Nefm
Gene name: neurofilament, medium polypeptide
Antibody: anti-neurofilament clone 2H3
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 3A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: facio-acoustic preganglion complex Present 3A
TS15: trigeminal preganglion Present 3A
Specimen 3B: embryonic day 9.5; Egr2tm1Grid/Egr2tm1Grid (more )
Structure Level Pattern Image Note
TS15: trigeminal preganglion Present 3B The expression domain is expanded in this mutant.
TS15: facio-acoustic preganglion complex Weak 3B
Specimen 3C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: acoustic ganglion Present 3C
TS17: cranial nerve Present 3C
TS17: facial ganglion Present 3C
TS17: glossopharyngeal ganglion Present 3C
TS17: trigeminal ganglion Present 3C
TS17: vagus ganglion Present 3C
TS17: 2nd branchial arch Present Regionally restricted 3C Expression is in the facial nerve innervating the arch.
Specimen 3D: embryonic day 10.5; Egr2tm1Grid/Egr2tm1Grid (more )
Structure Level Pattern Image Note
TS17: acoustic ganglion Present 3D The ganglia overlap in this mutant.
TS17: facial ganglion Present 3D The ganglia overlap in this mutant.
TS17: trigeminal ganglion Present 3D The ganglia overlap in this mutant.
TS17: cranial nerve Present 3D The glossopharyngeal and vagus nerves are fused in this mutant.
Specimen 3E: embryonic day 10.5; Egr2tm1Grid/Egr2tm1Grid (more )
Structure Level Pattern Image Note
TS17: acoustic ganglion Present 3E The ganglia overlap in this mutant.
TS17: facial ganglion Present 3E The ganglia overlap in this mutant.
TS17: trigeminal ganglion Present 3E The ganglia overlap in this mutant.
TS17: central nervous system nerve Present 3E The glossopharyngeal and vagus nerves are fused in this mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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