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Gene Expression Data
Assay Details
Assay
Reference: J:152821 Tian Y, et al., Essential role for the Pak4 protein kinase in extraembryonic tissue development and vessel formation. Mech Dev. 2009 Aug-Sep;126(8-9):710-20
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5779288
Gene symbol: Pecam1
Gene name: platelet/endothelial cell adhesion molecule 1
Antibody: Anti-CD31
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 2B +/+: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: yolk sac blood vessel Present 2B +/+
Specimen 2B -/-: embryonic day 10.5; Pak4tm1Amin/Pak4tm1Amin (more )
Structure Level Pattern Image Note
TS17: yolk sac blood vessel Weak 2B -/- There was poor vascular development, so there was only staining in a honeycomb-like primitive vascular plexus.
Specimen 7A -/-: embryonic day 9.5; Pak4tm1Amin/Pak4tm1Amin (more )
Structure Level Pattern Image Note
TS15: blood vessel Weak 7A -/- Middle , 7A -/- Upper , 7A -/- Lower Expression was dramatically reduced in the mutant due to defects/absence of branched networks of small vessels.
Specimen 7A +/+: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: blood vessel Present 7A +/+ Upper , 7A +/+ Middle , 7A +/+ Lower
Specimen 7B -/-: embryonic day 9.5; Pak4tm1Amin/Pak4tm1Amin (more )
Structure Level Pattern Image Note
TS15: blood vessel Weak 7B -/- Expression was dramatically reduced in the mutant due to defects/absence of branched networks of small vessels.
Specimen 7B +/+: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: blood vessel Present 7B +/+
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/28/2026
MGI 6.24 		The Jackson Laboratory