Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	P2ry1tm1.1(cre)Lbrl
Name:	purinergic receptor P2Y, G-protein coupled 1; targeted mutation 1.1, Stephen Liberles
MGI ID:	MGI:5776536
Synonyms:	P2ry1-ires-Cre
Gene:	P2ry1  Location: Chr3:60910216-60916403 bp, + strand  Genetic Position: Chr3, 29.24 cM, cytoband E1
Alliance:	P2ry1tm1.1(cre)Lbrl page

Germline Transmission:	Earliest citation of germline transmission: J:223335
Parent Cell Line:	W4 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Recombinase) Mutation:    Insertion   P2ry1tm1.1(cre)Lbrl expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse P2ry1 (MGI:105049)   Mutation details: A cassette encoding IRES, Cre recombinase, and an FRT-flanked neomycin selection cassette is inserted into the mouse P2ry1 locus 3 base pairs downstream of the coding sequence stop codon. (J:223335)

Activity:	Tissue activity of this recombinase allele
Driver:	P2ry1 (mouse) Summary of all recombinase alleles driven by P2ry1. Comparative matrix view of recombinase activities Alliance mouse P2ry1 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any P2ry1 Mutation:	31 strains or lines available

Original:	J:223335 Chang RB, et al., Vagal Sensory Neuron Subtypes that Differentially Control Breathing. Cell. 2015 Apr 23;161(3):622-33
All:	4 reference(s)