About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:192634 Kogo H, et al., HORMAD2 is essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity. Genes Cells. 2012 Nov;17(11):897-912
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5776046
Gene symbol: Atr
Gene name: ataxia telangiectasia and Rad3 related
Antibody: ATR (N-19; sc-1887) Antibody
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 2G Zygotene Hormad2-/-: postnatal adult; Hormad2tm1Kura/Hormad2tm1Kura (more )
Note: Zygotene stage spermatocytes. Triple labeled: green - Atr; red - Hormad2 (assay MGI:5776045); blue - DAPI.
Structure Level Pattern Image Note
TS28: spermatocyte Present Regionally restricted 2G Zygotene Hormad2-/-
Specimen 2G Pachytene-1 Hormad2-/-: postnatal adult; Hormad2tm1Kura/Hormad2tm1Kura (more )
Note: Very early pachytene stage spermatocytes. Triple labeled: green - Atr; red - Hormad2 (assay MGI:5776045); blue - DAPI.
Structure Level Pattern Image Note
TS28: spermatocyte Present Regionally restricted 2G Pachytene-1 Hormad2-/-
Specimen 2G Pachytene-2 Hormad2-/-: postnatal adult; Hormad2tm1Kura/Hormad2tm1Kura (more )
Note: Early pachytene stage spermatocytes. Triple labeled: green - Atr; red - Hormad2 (assay MGI:5776045); blue - DAPI.
Structure Level Pattern Image Note
TS28: spermatocyte Present Regionally restricted 2G Pachytene-2 Hormad2-/-
Specimen 2G Zygotene Wild-type: postnatal adult (more )
Note: Zygotene stage spermatocytes. Triple labeled: green - Atr; red - Hormad2 (assay MGI:5776045); blue - DAPI.
Structure Level Pattern Image Note
TS28: spermatocyte Present Regionally restricted 2G Zygotene Wild-type
Specimen 2G Pachytene-1 Wild-type: postnatal adult (more )
Note: Very early pachytene stage spermatocytes. Triple labeled: green - Atr; red - Hormad2 (assay MGI:5776045); blue - DAPI.
Structure Level Pattern Image Note
TS28: spermatocyte Present Regionally restricted 2G Pachytene-1 Wild-type
Specimen 2G Pachytene-2 Wild-type: postnatal adult (more )
Note: Early pachytene stage spermatocytes. Triple labeled: green - Atr; red - Hormad2 (assay MGI:5776045); blue - DAPI.
Structure Level Pattern Image Note
TS28: spermatocyte Present Regionally restricted 2G Pachytene-2 Wild-type
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory