Tg(CAG-HSPB1)HPks
Transgene Detail
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| Symbol: |
Tg(CAG-HSPB1)HPks |
| Name: |
transgene insertion H, Nick Parkinson |
| MGI ID: |
MGI:5775094 |
| Synonyms: |
chk.actin-HSP27 (WT), HSP27 WT High copy line, PCAGGS-HSP27-WT-HIGH-COPY |
| Transgene: |
Tg(CAG-HSPB1)HPks Location: unknown
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| Alliance: |
Tg(CAG-HSPB1)HPks page
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| Strain of Origin: |
Not Specified
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| Transgene Type: |
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Transgenic (Humanized sequence, Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(CAG-HSPB1)HPks expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
HSPB1 (3315) |
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Mutation details: The transgene comprises the coding sequence for wild-type human heat shock protein family B (small) member 1 (HSPB1) downstream of the "CAG promoter" -- which consists of the cytomegalovirus immediate early (CMV-EI) enhancer followed by a 1.3-kb DNA segment including the promoter, first exon and first intron of the chicken beta-actin gene, with the 3' splice junction sequence replaced by that of the rabbit hemoglobin beta gene -- and followed by the rabbit beta-hemoglobin polyadenylation signal and 3' flanking sequence. Heterozygous mice of this high copy number line carry approximately 35 copies of the transgene.
(J:82809)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 2 strains available
Cell Lines: 0 lines available
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| Original: |
J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013; |
| All: |
1 reference(s) |
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Analysis Tools
