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Gene Expression Data
Assay Details
Assay
Reference: J:231044 Gage PJ, et al., Mouse Models for the Dissection of CHD7 Functions in Eye Development and the Molecular Basis for Ocular Defects in CHARGE Syndrome. Invest Ophthalmol Vis Sci. 2015 Dec;56(13):7923-30
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5774854
Gene symbol: Tubb3
Gene name: tubulin, beta 3 class III
Antibody: anti-neuronal B-tubulin
Detection system: Secondary antibody
Results
Specimen 5M: embryonic day 12.5 (more )
Note: littermates were used for controls; their exact genotype was not detailed
Structure Level Pattern Image Note
TS20: neural retinal epithelium Present Patchy 5M Expression is present in forming retinal ganglion cells.
Specimen 5N: embryonic day 12.5; Chd7tm1.1Dmm/Chd7tm1.1Dmm, Tg(rx3-icre)1Mjam/0 (more )
Note: Conditional mutant. these are neural ectoderm-specific knockout embryos
Structure Level Pattern Image Note
TS20: neural retinal epithelium Present 5N Expression is present in forming retinal ganglion cells; there are extreme morphological changes in the mutants.
Specimen 5O: embryonic day 12.5; Chd7tm1.1Dmm/Chd7tm1.1Dmm, Tg(rx3-icre)1Mjam/0 (more )
Note: Conditional mutant. these are neural ectoderm-specific knockout embryos
Structure Level Pattern Image Note
TS20: neural retinal epithelium Present Patchy 5O Expression is present in forming retinal ganglion cells; there are extreme morphological changes in the mutants.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
MGI 6.24 		The Jackson Laboratory