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Gene Expression Data
Assay Details
Assay
Reference: J:231044 Gage PJ, et al., Mouse Models for the Dissection of CHD7 Functions in Eye Development and the Molecular Basis for Ocular Defects in CHARGE Syndrome. Invest Ophthalmol Vis Sci. 2015 Dec;56(13):7923-30
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5774852
Gene symbol: Vsx2
Gene name: visual system homeobox 2
Antibody: anti-Vsx2
Detection system: Secondary antibody
Results
Specimen 5G: embryonic day 12.5 (more )
Note: littermates were used for controls; their exact genotype was not detailed
Structure Level Pattern Image Note
TS20: neural retinal epithelium Present 5G

Specimen 5H: embryonic day 12.5; Chd7tm1.1Dmm/Chd7tm1.1Dmm, Tg(rx3-icre)1Mjam/0 (more )
Note: Conditional mutant. these are neural ectoderm-specific knockout embryos
Structure Level Pattern Image Note
TS20: neural retinal epithelium Present 5H Expression is seen in the expected location; there are extreme morphological changes in the mutants.

Specimen 5I: embryonic day 12.5; Chd7tm1.1Dmm/Chd7tm1.1Dmm, Tg(rx3-icre)1Mjam/0 (more )
Note: Conditional mutant. these are neural ectoderm-specific knockout embryos
Structure Level Pattern Image Note
TS20: neural retinal epithelium Present 5I Expression is seen in the expected location; there are extreme morphological changes in the mutants.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory