Pax6 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:231044 Gage PJ, et al., Mouse Models for the Dissection of CHD7 Functions in Eye Development and the Molecular Basis for Ocular Defects in CHARGE Syndrome. Invest Ophthalmol Vis Sci. 2015 Dec;56(13):7923-30
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:5774850
Gene symbol:	Pax6
Gene name:	paired box 6

Antibody:	anti-Pax6
Detection system:	Secondary antibody

Results

Specimen 5D: embryonic day 12.5 (more

)
Note: littermates were used for controls; their exact genotype was not detailed

Structure	Level	Image	Note
TS20: retina	Present	5D	Expression is present in both layers of the optic cup.
TS20: optic stalk	Absent	5D
TS20: cornea epithelium	Present	5D	Expression is present in the ocular surface ectoderm.
TS20: lens vesicle	Present	5D

Specimen 5E: embryonic day 12.5; Chd7^tm1.1Dmm/Chd7^tm1.1Dmm, Tg(rx3-icre)1Mjam/0 (more

)
Note: Conditional mutant. these are neural ectoderm-specific knockout embryos

Structure	Level	Pattern	Image	Note
TS20: retina	Present		5E	Expression is seen in the expected locations; there are extreme morphological changes in the mutants.
TS20: optic stalk	Absent		5E	Expression is seen in the expected locations; there are extreme morphological changes in the mutants.

Specimen 5F: embryonic day 12.5; Chd7^tm1.1Dmm/Chd7^tm1.1Dmm, Tg(rx3-icre)1Mjam/0 (more

)
Note: Conditional mutant. these are neural ectoderm-specific knockout embryos

Structure	Level	Pattern	Image	Note
TS20: retina	Present		5F	Expression is seen in the expected locations; there are extreme morphological changes in the mutants.
TS20: optic stalk	Absent		5F	Expression is seen in the expected locations; there are extreme morphological changes in the mutants.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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